Associate Director/Director, Formulation & Downstream Process Development

Pivotal; San Diego (CA); On-site; USD 65,000 - 100,000; Full time

Benefits offered by this job

Competitive salary

Equity

Medical, Dental, and Vision

401k Match of 4%

Paid Time Off

Job summary

Pivotal in San Diego, CA is seeking a skilled Research Associate for Formulation Development. This role involves designing, executing, and analyzing protocols for lipid nanoparticle (LNP) drug delivery systems aimed at gene editing.

The ideal candidate will have 3+ years of experience in pharmaceutical formulation and experience with techniques such as DLS and electron microscopy. A competitive salary ranging from $65,000 to $100,000, along with an exceptional benefits package, awaits the right candidate.

Qualifications

• Bachelor's degree or higher in Chemistry, Pharmaceutics, Biochemistry, Biomedical Engineering, Chemical Engineering, or a related field.
• 3+ years of experience in pharmaceutical formulation, with a focus on lipid nanoparticle drug delivery systems.
• Experience with techniques such as DLS, zeta potential measurement, and other analytical tools.

Responsibilities

• Develop lipid nanoparticle (LNP) formulations for gene editing applications.
• Conduct experiments to optimize formulation parameters such as particle size, encapsulation efficiency, and stability.
• Collaborate with preclinical and clinical teams to ensure successful translation of formulations.

Skills

Pharmaceutical formulation

Analytical characterization

Team collaboration

Problem-solving

Education

Bachelor's degree in Chemistry or related field

Tools

Dynamic light scattering (DLS)

Electron microscopy

Job description

Research Associate, Formulation Development

Location: San Diego, CA

Job Type: Full-Time, Onsite

About Us

We are an innovative, stealth-mode biotech focused on developing best-in-class delivery for in vivo gene editing.

Job Summary

We are seeking a highly motivated and skilled individual to join our team as a Research Associate in Formulation Development. The successful candidate will be responsible for designing, executing, analyzing, and making recommendations on research protocols for lipid nanoparticle (LNP) drug delivery systems aimed at gene editing. Title level and salary will be commensurate with experience.

Responsibilities

• Develop lipid nanoparticle (LNP) formulations for gene editing applications.
• Conduct experiments to optimize formulation parameters such as particle size, encapsulation efficiency, and stability.
• Optimize production processes to improve yields and scalability.
• Troubleshoot and resolve issues related to formulation processes.
• Perform analytical characterization of LNPs using techniques such as dynamic light scattering (DLS), zeta potential measurement, and electron microscopy.
• Support in vitro and in vivo studies to evaluate the efficacy and safety of LNP formulations.
• Collaborate with preclinical and clinical teams to ensure successful translation of formulations.
• Maintain accurate and detailed laboratory records.
• Prepare technical reports and presentations to communicate findings.
• Stay current with advancements in LNP technologies and methodologies.

Qualifications

• Bachelor's degree or higher in Chemistry, Pharmaceutics, Biochemistry, Biomedical Engineering, Chemical Engineering, or a related field.
• 3+ years of experience in pharmaceutical formulation, with a focus on lipid nanoparticle drug delivery systems.
• Experience with techniques such as DLS, zeta potential measurement, and other analytical tools used in nanoparticle characterization.
• Strong analytical and problem-solving skills.
• Excellent communication and teamwork abilities.
• Ability to work independently and manage multiple tasks effectively.

Preferred Qualifications

• GMP production experience.
• Familiarity with regulatory requirements and quality control in bioprocessing.

Benefits

• Competitive salary, equity, and benefits package.
• Opportunities for professional growth and development.
• Fast paced collaborative and innovative work environment.
• We offer an exceptional benefits package to include Medical, Dental, Vision, Life, Disability, a 401k Match of 4%, Paid Time Off and Equity.

Equal Opportunity Employer

We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran, or disability status.

Salary Range

$65,000 - $100,000