Research Associate Co-Op, In Vivo Bone Pharmacology

Keros Therapeutics; Lexington (MA); On-site; USD 39,000 - 44,000; Part time

Job summary

Keros Therapeutics is seeking a motivated student for a 6-month co-op in our preclinical research group, focusing on cardiovascular abnormalities and bone diseases.

You will gain hands-on experience with in vivo and ex vivo methods, learn experimental design and data interpretation, and contribute to the discovery of next-generation therapies in a collaborative, cross-functional team.

Qualifications

• Pursuing a degree in physiology, biology, biochemistry, or related fields.
• Ability to work in a cross-functional team and independently with supervision.
• Strong communication and organizational skills; proficient with MS Office and data plotting.

Responsibilities

• Supports In Vivo studies with rodents: handling, dosing (IP/IV/SC/PO), bleeding and tissue collection.
• Performs basic molecular biology techniques: RNA isolation, qPCR, Western Blot, ELISA.
• Maintains detailed records of procedures, results and analyses in lab notebooks.
• Participates in experimental planning, data interpretation and presents findings at team meetings.

Skills

Physiology

Biology

Biochemistry

Molecular biology

Communication

Organization

MS Office

Data plotting

Education

Students major in physiology, biology, biochemistry, or related majors

Tools

RNA isolation

qPCR

Western Blot

ELISA

DEXA

microCT

Job description

At Keros, our mission is to deliver significant clinical benefit to a wide range of patients with disorders that are linked to dysfunctional signaling of the transforming growth factor-beta (TGF-ß) family of proteins. With a focus on developing differentiated product candidates that are designed to alter TGF-β signaling, we aim to target the pathways critical for the growth, repair and maintenance of blood cells and a number of tissues, including bone, skeletal muscle, adipose and heart tissue. We believe our product candidates have the potential to unlock the full therapeutic benefits of modulating the TGF-β superfamily and provide disease-modifying benefit to patients.

Job Summary

We are looking for a highly motivated and innovative student to join the cardiopulmonary and bone team for a 6-month co-op role in our preclinical research group focusing on cardiovascular abnormalities and bone diseases. This is a fantastic opportunity to make a significant impact on the discovery and development of next-generation therapies. The candidate will gain valuable industry experience and receive extensive training in vivo and ex vivo research. In addition, a successful candidate will be inquisitive about science and capable of troubleshooting by reviewing literature/colleagues and designing experiments to test hypotheses.

Primary Responsibilities

• Supports In Vivo studies: willingness to work with rodents. This includes animal handling, dosing (IP/IV/SC/PO), bleeding, necropsy, tissue collection and wet lab sample processing
• Basic molecular biology techniques: RNA isolation, qPCR, Western Blot, ELISA
• Maintains detailed and accurate records of experimental procedures, results, and analysis in laboratory notebooks
• Participates in experimental planning, interpretation of data and present findings at team meetings

Core Competencies (Required Skills)

• Physiology, biology, biochemistry and molecular biology
• Ability to work as part of a cross-functional team as well as independently with supervision
• Excellent communication and organization skills, good working knowledge of MS office, and data plotting

Preferred Skills

• Interest in cardiovascular and bone physiology
• Prior experience with laboratory animals (rodents), open to learning and perfecting rodent handling and dosing techniques
• Familiarity with basic molecular biology techniques including RNA isolation, qPCR, Western Blot, ELISA
• Experience working with imaging and image analysis such as DEXA and microCT is a plus

Education Requirements

• Students with a major in physiology, biology, biochemistry, or related majors

This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, and other relevant factors.Potential base pay range $28—$32 USD

Our Diversity, Equity & Inclusion Mission Statement:

Keros is an inclusive company. We believe that diversity drives innovation. We continue to build an inclusive culture that encourages, supports, and celebrates the diverse voices of our employees. As such, Keros takes a holistic approach in mentoring, coaching, and developing all of our Keros team members.

Keros Therapeutics is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected veteran status, or any other characteristic protected by applicable federal, state, or local law.

Recruitment & Staffing Agencies

Keros Therapeutics does not accept unsolicited resumes from any source other than the candidate directly. Any unsolicited submission by an agency to Keros is prohibited. Any resume submitted by an agency without a signed contract or expressed consent by a member of the Keros Therapeutics Human Resources Department, will be considered property of Keros Therapeutics, and no fee shall be owed with respect thereto.