Research Associate 1-Hematology

Ohio State University

Columbus, Northern (OH, KY)

Hybrid

USD 52,000 - 72,000

Full time

9 days ago
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Job summary

Ohio State University is seeking a Research Associate 1 in Hematology to design and manage preclinical studies in a foundational lab within the Hematology/Oncology program. The role collaborates with the PI to implement study goals, oversee experiments, and contribute to publications and grant proposals.

The candidate should have a Bachelor's degree in biological/health sciences and at least three years of relevant research experience, including patient-derived xenograft mouse models for T-cell

Qualifications

  • Bachelor's degree in a biological/health science or equivalent required.
  • Three years of relevant biological/health research experience required, including patient-derived xenograft mouse models for T-cell acute lymphoblastic leukemia.
  • Experience with preparation of patient samples and in vitro/in vivo models on combined therapies and CK2/Ikaros axis in acute leukemia is priority.
  • Desired: experience with mouse cancer models, especially hematological malignancies; familiarity with flow cytometry, tissue handling, and human sample handling.
  • Advanced degree preferred.

Responsibilities

  • Design, execute, and manage complex laboratory experiments.
  • Plan and perform molecular, cellular, and preclinical animal studies.
  • Coordinate data processing, analysis, and interpretation of results.
  • Develop new/revised research methods, controls, and standards.
  • Assist in grant writing and preparing research papers for publication and conferences.
  • Train staff and manage daily lab operations; procure equipment and oversee service contracts.
  • Ensure OSHA compliance and safety procedures; manage budgeting and expenses.
  • Present results at national/international conferences.

Skills

Flow cytometry
Mouse handling
Cell culture techniques
Survival surgeries
qChIP techniques
CUT & TAG techniques
Immunology techniques
Metabolism techniques

Education

Bachelor's degree in biological/health sciences

Tools

Patient-derived xenograft mouse models
Basic lab equipment for in vivo work

Job description

Research Associate 1-Hematology## Department:Medicine | IM Hematology## Scope/Summary:Research Associate designs, executes, and manages research projects, conducting preclinical studies in a foundational (basic) biological and health science research laboratory in the Hemaotlogy/Oncology laboratory of Dr. Chunhua Song. Collaborates with principal investigator (PI, Chunhua Song) to develop and implement goals and objectives of studies. Conceptualizes, designs, and executes complex laboratory experiments. Plans and executes advanced molecular, cellular, and preclinical animal study techniques. Plans, coordinates and oversees processing and analysis of data; analyzes and interprets research data. Develops and implements new and/or revised research methodology and techniques. Plans and tests experimental designs, sampling techniques, and analytical methods and develops and establishes research controls, criteria and standards. Performs critical analysis of literature relevant to research. Collaborates with the principal investigator to write and prepare research papers and manuscripts for publication and presentation at national conferences and workshops, and in the writing of project reports, articles and other documents. Attends and presents research results at national and international scientific conferences, workshops and seminars.Assists with development, writing and preparation of grant proposals to obtain new or renewal of extramural funding in support of research. Investigates, identifies and recommends possible sources of research funding. Participates in developing and managing grant budgets, monitors expenses. Monitors and enforces laboratory safety procedures to ensure compliance with OSHA regulations, as well as local, state, and federal regulations, including proper disposal and maintenance of regulated materials. Trains research staff and manages daily operations of the laboratory. Oversees and initiates procurement of lab supplies and equipment. Provides technical assistance and supervision of equipment. Negotiates and oversees equipment service contracts and repairs.**Minimum Qualifications:**A Bachelor’s degree in an appropriate biological/health science or an equivalent combination of education and experience is required. Three years of relevant experience in a biological/health research capacity is required, particularly with patient-derived xenograft mouse models for T-cell acute lymphoblastic leukemia and preparation of patient samples. Strong experience in vitro and in vivo models on combined therapies and the CK2/Ikaros axis in acute leukemia is a priority.**Desired Qualifications:**Experience working with mouse models of cancer, especially hematological malignancies, is highly desirable. Must be familiar with flow cytometry techniques, mouse tissue handling, and human sample handling. Must be extremely comfortable working/handling mice and performing survival surgeries. Familiarity with cell-culture techniques, CUT & TAG and qChIP techniques, Basic Immunology-related techniques, and metabolism-related techniques is desirable. Advanced degree preferred.**Career Roadmap:****Function**: Research and Scholarship**Subfunction**: Research**Band**: Specialized**Level**: 1## Additional Information:## Location:Biomedical Research Tower (0112)## Position Type:Regular## Scheduled Hours:40## **Shift:**First Shift
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