Research Associate

Syenex; Evanston (IL); In loco; USD 65.000 - 90.000; Tempo pieno

Descrizione del lavoro

Syenex, Inc is seeking a Research Associate to join the Discovery Team to support design, production, optimization, and screening of novel delivery vectors for cell and gene therapy. You will work on characterization, in vitro assay development, and cell line maintenance to advance multiple delivery platforms.

The role involves collaboration, protocol development, and presenting results. A biology/biochemistry background with hands-on lab experience and strong attention to data quality are

Competenze

• Bachelor’s degree with 1–4 years lab experience or MS with 1–2 years experience.
• Experience maintaining mammalian cells in culture using standard techniques.
• Strong understanding of molecular biology and cell biology.

Mansioni

• Produce and test novel vector designs for mammalian cell delivery using flow cytometry, imaging, and genomic analysis.
• Characterize gene and protein expression in mammalian cells using flow cytometry, microscopy, qPCR, ELISA.
• Maintain mammalian cell cultures.
• Perform cloning and plasmid preparation.
• Participate in experimental design, optimization, and method development.
• Support customer LVV production and characterization.
• Follow SOPs and develop new protocols when necessary.
• Collaborate to generate and screen novel delivery vehicles.
• Maintain records of samples through database curation and electronic tracking.
• Document and present findings to the R&D team and wider company.

Conoscenze

Flow cytometry

Mammalian cell culture

Molecular biology

Cloning

Transfection

Transduction

Protein characterization

Formazione

Bachelor’s degree

MS in Biology/Biochemistry/Engineering

Strumenti

Flow cytometer

qPCR machine

ELISA plate reader

Western blot equipment

Descrizione del lavoro

About the role

We are seeking a Research Associate to join the Discovery Team and support the design, production, optimization, and screening of novel delivery vectors for cell and gene therapy. Characterization and evaluation of those delivery vehicles and in vitro assay development will be key elements of the position, along with primary cell and cell line maintenance and culturing. This individual will join a dynamic, rapidly growing, and highly collaborative team that combines significant biological discovery experience with pioneering discoveries driving multiple delivery platforms.

What you’ll do

• Produce and test novel vector designs for mammalian cell delivery via flow cytometry, imaging, and genomic analysis techniques.
• Characterize gene and protein expression in mammalian cells using flow cytometry, microscopy, qPCR, ELISA, etc.
• Maintain mammalian cell cultures.
• Perform molecular biology-based cloning and plasmid preparation.
• Participate in experimental design, optimization, and method development.
• Support customer LVV production and characterization.
• Follow Standard Operating Procedures and develop new protocols when necessary.
• Work collaboratively to generate and screen novel delivery vehicles.
• Maintain accurate records of experimental samples through database curation and electronic tracking.
• Document and present findings to the R&D team and wider company.

What you’ll bring

• Bachelor’s plus 1-4 years laboratory experience in an academic or industry setting or MS in scientific related field (Biology, Biochemistry, Engineering) with 1-2 years experience
• Experience maintaining various mammalian cells in culture using standard techniques
• Understanding of molecular biology and cell biology
• Experience with viral vectors and/or nanoparticles, including concentration and purification methods
• Experience with mammalian cell transfection and transduction
• Experience with flow cytometry
• Experience with protein characterization (e.g., ELISA, western-blots, BLI)
• Highly motivated with a strong desire to learn and contribute to team science
• Strong work ethic with attention to detail and data quality
• Demonstrated ability in working in a fast-paced, collaborative, and technical environment

Why Syenex

You will contribute to the early phase research of a company whose delivery technologies enable more cures to reach more people. You will see your work being adopted by customers and brought to the clinic. You be exposed to a wide range of technologies and will have the opportunity to make significant contributions to an early-stage team already trusted by partners across biopharma and academia. We encourage you to apply even if you do not believe you meet every single qualification. Research shows that strong candidates—particularly those from underrepresented groups—are prone to doubting the strength of their candidacy, so we urge you not to exclude yourself prematurely.