Research Associate

University of Colorado System; Aurora (CO); On-site; USD 68,000 - 92,000; Full time

Benefits offered by this job

Medical plans

Dental plans

Retirement plan

Paid time off

Holidays

Tuition benefit

ECO Pass

Job summary

University of Colorado Anschutz in Aurora, CO, invites applications for a Research Associate to conduct basic and translational research on idiopathic pulmonary fibrosis using 3D cell culture and omics approaches. You will explore MUC5B expression dynamics and epigenetic regulation while combining experimental and computational methods.

The role focuses on mechanistic lung fibrosis determinants, with publications and collaborations across divisions.

Qualifications

• Ph.D. in Cell Biology, Molecular Biology or a related field.
• Extensive experience with laboratory techniques and equipment.
• Proven track record of published research.
• Experience with advanced microscopy (preferred).
• Experience with tissue or organoid culture (preferred).
• Familiarity with bioinformatics tools (preferred).

Responsibilities

• Perform experiments to study lung epithelial cells alterations under pro-fibrotic conditions.
• Analyze and interpret multi-omics biological data.
• Write research papers and reports for publication.
• Collaborate with other scientists and researchers.
• Maintain and operate laboratory equipment.
• Teaching and supervising students or junior staff.
• Present findings at scientific conferences and meetings.
• Ensure compliance with laboratory safety standards.
• Apply for research grants and funding.
• Stay updated with the latest scientific literature and advancements.

Skills

Analytical skills

Problem-solving

Written communication

Verbal communication

Team collaboration

Education

Ph.D. in Cell Biology or Molecular Biology

Job description

University of Colorado Anschutz

Department: Medicine/Pulmonary, Allergy, and Critical CareMedicine

Job Title: Research Associate

Position #00853681 – Requisition #41336

Job Summary:

The research associate will conduct basic and translationalresearch in idiopathic pulmonary fibrosis, focusing on 3D cellculture models, molecular determinants of cell fate, epigenetics,and transcriptional regulation of fibrosis-related genes. Theoverall aim of this research will be to investigate ectopicexpression of airway mucin MUC5B in alveolar epithelial cells andto determine the mechanisms that lead to lung fibrosis. Theresearch associate will use small-molecule and geneticknockdown/overexpression approaches to manipulate expression ofMUC5B gene and relevant transcription factors. The researchassociate will induce perturbations into 3D culture models toreproduce molecular profile of epithelial cells observed infibrotic lungs. The research associate will assay the resultsthrough multi-omics experiments. The research associate willcombine experimental and computational approaches to investigatealveolar cell plasticity and to control cell fates. Our ultimategoal is to understand the early mechanistic determinants of lungfibrosis and to alter trajectories of cells development to preventprogression of fibrosis.

Key Responsibilities :

• Performing experiments to study lung epithelial cellsalterations under pro-fibrotic conditions
• Analyzing and interpreting multi-omics biological data
• Writing research papers and reports for publication
• Collaborating with other scientists and researchers
• Maintaining and operating laboratory equipment
• Teaching and supervising students or junior staff
• Presenting findings at scientific conferences andmeetings
• Ensuring compliance with laboratory safety standards
• Applying for research grants and funding
• Staying updated with the latest scientific literature andadvancements

Work Location:

Onsite – this role is expected to work onsite and is located in Aurora, CO.

Why Join Us:

About the Division of Pulmonary, Allergy, and Critical Care Medicine:

Thank you for your interest in the Division of Pulmonary, Allergy,and Critical Care Medicine at the University of Colorado! Our over140 faculty are located across four sites: the University ofColorado Anschutz Medical Campus, National Jewish Health, DenverHealth, and the VA Eastern Colorado Health Care System.

We are very proud of our long and illustrious history. Many seminaldiscoveries in pulmonary and critical care medicine occurred herein Denver, including advances in tuberculosis, interstitial lungdisease, airway disease, cancer, and critical care. Many of ourformer trainees have taken leadership roles in academic medicine,including Division and Department Chairs, Deans, and AmericanThoracic Society Presidents.

We continue to enhance all aspects of our division and trainingprogram, and as a result, we have seen tremendous and sustainedgrowth. The clinical practice sites have built new hospitals, andthere are multiple new research buildings across the campuses. Wehave been fortunate to recruit tremendous new faculty members whileretaining many of our former trainees.

About the University of Colorado Anschutz MedicalCampus:

The University of Colorado Anschutz Medical Campus is a world-classmedical destination at the forefront of transformative science,medicine, education, and patient care. The campus encompasses theUniversity of Colorado health professional schools, more than 60centers and institutes, and two nationally ranked independenthospitals - UCHealth University of Colorado Hospital and Children's Hospital Colorado - that treat more than two millionadult and pediatric patients each year.

Innovative, interconnectedand highly collaborative, the University of Colorado AnschutzMedical Campus delivers life-changing treatments, patient care andprofessional training and conducts world-renowned research fueledby over $757 million in research grants. For more information,visit www.cuanschutz.edu.

There are many additional perks & programs with CU Advantage.

Why work for the University?

We have AMAZING benefits and offer exceptional amounts of holiday,vacation and sick leave! The University of Colorado offers anexcellent benefits package including:

• Medical: Multiple plan options
• Dental: Multiple plan options
• Additional Insurance: Disability, Life, Vision
• Retirement 401(a) Plan: Employer contributes 10% of your grosspay
• Paid Time Off: Accruals over the year (based on percentage oftime)
• Vacation Days: 22/year (maximum accrual 352 hours)
• Sick Days: 15/year (unlimited maximum accrual)
• Holiday Days: 11/year
• Tuition Benefit: Employees have access to this benefit on allCU campuses
• ECO Pass: Reduced rate RTD Bus and light rail service

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time ofhire.

• Ph.D. in Cell Biology, Molecular Biology or a relatedfield
• Extensive experience with laboratory techniques andequipment
• Proven track record of published research

Preferred Qualifications:

• Experience with advanced microscopy techniques
• Experience with tissue culture
• Experience with organoid culture models
• Familiarity with bioinformatics tools and software

Knowledge, Skills, and Abilities:

• Strong analytical and problem-solving skills
• Excellent written and verbal communication skills
• Ability to work collaboratively in a team environment

Screening of Applications Begins:

Immediately and continues until October 11, 2026.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as $80,000.

The above salary range (or hiring range) represents theUniversity's good faith and reasonable estimate of the range ofpossible compensation at the time of posting. This position is noteligible for overtime compensation unless it is non-exempt.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plansand retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

Equal Employment Opportunity Statement:

The University of Colorado (CU) is an Equal Opportunity Employerand complies with all applicable federal, state, and local lawsgoverning nondiscrimination in employment. We are committed tocreating a workplace where all individuals are treated with respectand dignity, and we encourage individuals from all backgrounds toapply, including protected veterans and individuals withdisabilities.

ADA Statement:

The University will provide reasonable accommodations to applicantswith disabilities throughout the employment application process. Torequest an accommodation pursuant to the Americans withDisabilities Act, please contact the Human Resources ADACoordinator at [e-mail].

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated toensuring a safe and secure environment for our faculty, staff,students and visitors. To assist in achieving that goal, we conductbackground investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19virus and other vaccine preventable diseases. If you work, visit, or volunteerin healthcare facilities or clinics operated by our affiliatedhospital or clinical partners or by CU Anschutz, you will berequired to comply with the vaccination and medical surveillancepolicies of the facilities or clinics where you work, visit, orvolunteer, respectively. In addition, if you work in certainresearch areas or perform certain safety sensitive job duties, youmust enroll in the occupational health medical surveillance program.