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University of Virginia seeks a Research Assistant Professor to work in the Janes laboratory within the Biomedical Engineering program. The role focuses on experimental testing and validation of subcellular models of RNA virus infections, aiming to elucidate virus entry, replication, and release in human cells.
The candidate will integrate computational and experimental approaches, interact with graduate students, and contribute to grant writing and publishing efforts.
The Department of Biomedical Engineering at the University of Virginia seeks a Research Assistant Professor to work in the Janes laboratory (Systems bioengineering approaches for cancer and virology). This position will focus on experimental testing and validation of subcellular models of RNA virus infections in humans. The primary goal is to establish virus-host interaction at the level of virus entry, replication and release. The applicant will be expected to integrate computational and experimental methodologies to predict infectivity and anti-viral responses to prevalent RNA viruses.
The applicant will be expected to interact with graduate students, teach and train students, write grants to secure support for independent activities, and publish.
Additionally, the applicant should be familiar with RNA isolation from viruses, mammalian cell lines and human blood/serum, diagnostic PCR, semi-quantitative and quantitative RT-PCR, mRNA splicing assay, cloning, in vitro transcription, in vitro coupled transcription and translation, RNA-immunoprecipitation, immunoprecipitation, immunofluorescence, transfection, nucleofection, transduction using retroviruses, generation of G418 resistant stable cell line. Experience with data analysis and machine learning models will be viewed favorably.
QUALIFICATIONS : A Ph.D. in Molecular Virology specializing in the biology of RNA viruses and deep understanding of subcellular RNA virus infection mechanisms in human, virus replication complex assembly, RNA-protein interaction, RNA-FISH, cell biology, cancer biology, molecular biology, cell & tissue culture, advanced optical microscopy like Fluorescence Lifetime Imaging Microscopy (FLIM), Föster Resonace Energy Transfer (FRET), confocal laser microscopy, super-resolution microscopy, cellular metabolism, drug response assay.
Additionally, the applicant should be familiar with RNA isolation from viruses, mammalian cell lines and human blood/serum, diagnostic PCR, semi-quantitative and quantitative RT-PCR, mRNA splicing assay, cloning, in vitro transcription, in vitro coupled transcription and translation, RNA-immunoprecipitation, immunoprecipitation, immunofluorescence, transfection, nucleofection, transduction using retroviruses, generation of G418 resistant stable cell line. Experience with data analysis and machine learning models will be viewed favorably.
Experience managing multi-investigator collaborations; strong oral and written communication skills with a strong publication record and grant report experience in relevant fields; the capability to work effectively with undergraduate and graduate students, as well as colleagues from multiple disciplines.
This is a one-year appointment, which may be renewed contingent upon available funding and satisfactory performance.
The University will perform background checks on all new hires before employment.