Research Assistant II

Digitailor; Boston (MA); In loco; USD 42.000 - 60.000; Tempo pieno

Descrizione del lavoro

Harvard Medical School’s LSP-TPS Core Facility seeks a Research Assistant II to join an interdisciplinary team of biomedical scientists and software engineers. You will learn and perform spatial profiling assays on human tissue samples and model organisms, while gaining experience with AI-assisted data processing.

The role emphasizes organization, attention to detail, and strong communication, in a collaborative environment that values precision and scientific rigor.

Competenze

• Must be organized and detail-oriented.
• Excellent reasoning and communication skills.
• Ability to excel in a collaborative, interdisciplinary team.

Mansioni

• Perform spatial profiling assays and imaging following established protocols.
• Prepare and submit libraries for sequencing (NGS).
• Conduct quality control on antibodies and reagents.
• Train core users in routine workflows after training.
• Collect, process, and summarize experimental data for users.
• Maintain electronic lab notebook with accurate records.
• Create/update protocols and assist in experimental design.
• Maintain lab supplies and interface with vendors.
• Assist with simple clerical tasks and core invoicing under supervision.

Conoscenze

Detail oriented

Strong communication

Teamwork

Descrizione del lavoro

Company Description By working at Harvard University, you join a vibrant community that advances Harvard's world-changing mission in meaningful ways, inspires innovation and collaboration, and builds skills and expertise. We are dedicated to creating a diverse and welcoming environment where everyone can thrive.

Why Join

Harvard Medical School? Harvard Medical School's mission is to nurture a diverse, inclusive community dedicated to alleviating suffering and improving health and well-being for all through excellence in teaching and learning, discovery and scholarship, and service and leadership. You’ll be at the heart of biomedical discovery, education, and innovation, working alongside world-renowned faculty and a community dedicated to improving human health. This is more than a job - it’s an opportunity to shape the future of medicine. About the Harvard Program in Therapeutic Science: The Laboratory of Systems Pharmacology Tissue Profiling Service (LSP-TPS) Core Facility within the Harvard Program in Therapeutic Science at Harvard Medical School is seeking a Research Assistant II to join an interdisciplinary team of biomedical scientists and software engineers. Our team is dedicated to advancing the science needed for precision medicine approaches to drug discovery and patient care. The Core provides services to scientists and clinicians in the Boston area and beyond, providing access to innovative methods for studying human tissues and biopsies. These include cutting-edge spatial biology methods that provide unique insight into the molecular features of healthy and diseased tissues. These assays include multiplexed cyclic immunofluorescence and GeoMx Digital Spatial Profiling (DSP). Job Description Under the supervision of the LSP-TPS core director, the Research Assistant II will learn and perform spatial profiling assays on samples from human patients and model organisms. This position also offers the opportunity to learn how to process the resulting data using AI tools. The LSP-TPS Core is an intense and collaborative environment that handles clinical samples that are precious and difficult to replace. Thus, the successful candidate must be organized and detail-oriented, possess strong reasoning and communication skills, and excel at working in teams. Job-Specific

Responsibilities

• Perform CycIF, ORION, and GeoMX profiling assays following established protocols, such as: Immunofluorescence staining of samples on slides o Image slides using a variety of fluorescence- and brightfield-based microscopes and scanners.
• Prepare and submit libraries for Next Generation Sequencing (NGS).
• Perform quality control testing of antibodies and other reagents.
• Once trained, instruct core users in routine spatial profiling workflows.
• Collect, process, and summarize experimental data for core users.
• Maintain an electronic lab notebook and keep detailed, accurate, up-to-date records of all experiments.
• Create and update written protocols; collaborate to optimize experimental design and protocols; help draft scientific written reports.
• Maintain common lab supplies, equipment, and glass slide inventories; interface with vendor and service representatives.
• Help process core invoices and perform other simple clerical duties under the direction of senior core personnel.