Remote Regional Director of Clinical Operations

M3 USA Corporation; Los Angeles (CA); Remote; USD 130,000 - 160,000; Full time

Benefits offered by this job

401(k) with matching

Dental insurance

Disability insurance

Employee assistance program

Flexible spending account

Health insurance

Life insurance

Paid time off

Vision insurance

Job summary

M3 Wake Research is seeking a Regional Director of Clinical Operations to lead the site network across a defined region. You’ll oversee Site Directors and Site Managers, partner with principal investigators, and ensure enrollment, quality, and revenue goals are met.

This hands-on leadership role requires building strong teams, driving process improvements, and ensuring FDA/ICH-GCP compliance across multiple sites. The position is remote with up to 50% travel.

Qualifications

• Bachelor’s degree in science, nursing, or related field (equivalent combination of education, experience, and training considered)
• 7-10+ years of progressively responsible experience in clinical research or related operations
• 5+ years of people management experience
• Clinical experience across two or more therapeutic areas
• Experience with multi-site networks, SMOs, TMOs, or hospital-owned physician networks preferred
• Strong knowledge of FDA regulations, ICH-GCP, safety reporting, and investigational product handling
• Healthcare background in a line of business with direct patient care and physician collaboration
• Ability to make financially sound, defensible business decisions
• Strong communicator across sites, sponsors, CROs, and regulators
• Data-driven with a track record of developing and coaching talent

Responsibilities

• Lead, coach, and develop Site Directors and Site Managers, setting clear goals, KPIs, and expectations
• Step in as Interim Site Director during transitions and ensure site coverage
• Monitor operations and performance metrics to improve enrollment, quality, and protocol compliance
• Roll out network-wide processes, systems, and SOPs across sites
• Partner with site leadership on budgeting, forecasting, FTE planning, and margin management
• Review financial and operational reports to spot risks and trends early
• Collaborate with Marketing and Recruitment to strengthen enrollment strategy
• Support feasibility input and site capability assessments for BD
• Coordinate with Quality, Regulatory, and Clinical Affairs on audit readiness and PI oversight
• Build strong relationships with PIs and serve as regional escalation point for sponsor concerns
• Support hiring, onboarding, and staffing decisions for site teams
• Lead mid-year and annual performance reviews for direct reports

Skills

Leadership

Team management

Regulatory knowledge

Communication

Clinical operations

Education

Bachelor’s degree in science or related field

Job description

M3 Wake Research is seeking a Regional Director of Clinical Operations to lead the site network across a defined region. You’ll oversee Site Directors and Site Managers, partner with principal investigators, and ensure enrollment, quality, and revenue goals are met.

This hands-on leadership role requires building strong teams, driving process improvements, and ensuring FDA/ICH-GCP compliance across multiple sites. The position is remote with up to 50% travel.