Remote Regional Director, Clinical Operations – Multi-Site

M3USA; Texas; Remote; USD 150,000 - 190,000; Full time

Benefits offered by this job

401(k)

Dental insurance

Health insurance

Life insurance

Paid time off

Vision insurance

Job summary

M3 Wake Research is seeking a Regional Director of Clinical Operations to lead clinical operations across a regional network of sites. You will oversee Site Directors and Site Managers, partner with principal investigators, and ensure enrollment, quality, and revenue goals are met.

This is a remote leadership role with up to 50% travel. You will drive performance, coach teams, implement SOPs, manage budgeting and forecasting, and coordinate with Quality, Regulatory, and Clinical Affairs to

Qualifications

• Bachelor’s degree in science, nursing, or related field.
• 7–10+ years in clinical research or related operations.
• 5+ years of people management experience.
• Clinical experience across two or more therapeutic areas.
• Experience with multi-site networks, SMOs, TMOs, or hospital-owned physician networks.
• Strong knowledge of FDA regulations, ICH-GCP, safety reporting, and investigational product handling.
• Data-driven with a track record of developing and coaching talent.

Responsibilities

• Lead Site Directors and Site Managers, setting clear goals and KPIs.
• Step in as Interim Site Director or arrange coverage during transitions.
• Monitor operations to improve efficiency, enrollment, and protocol compliance.
• Roll out network-wide processes, systems, and SOPs.
• Partner with site leadership on budgeting, forecasting, and margin management.
• Review financial and operational reports to spot risks and trends early.
• Work with Marketing and Participant Recruitment to strengthen enrollment strategy.
• Support BD with feasibility input and site capability assessments.
• Coordinate audit readiness with Quality, Regulatory, and Clinical Affairs.
• Build strong relationships with PIs and serve as the regional escalation point for investigator and sponsor concerns.
• Support hiring, onboarding, and staffing decisions for site-level teams.
• Lead mid-year and annual performance reviews for your direct reports.

Skills

Leadership

People management

Communication

Budgeting

Forecasting

Data-driven

Clinical operations

Education

Bachelor's degree in science or related field

Job description

M3 Wake Research is seeking a Regional Director of Clinical Operations to lead clinical operations across a regional network of sites. You will oversee Site Directors and Site Managers, partner with principal investigators, and ensure enrollment, quality, and revenue goals are met.

This is a remote leadership role with up to 50% travel. You will drive performance, coach teams, implement SOPs, manage budgeting and forecasting, and coordinate with Quality, Regulatory, and Clinical Affairs to