Remote Lead Clinical Data Manager – Oncology & Early-Phase

Tempus; Northern (KY); Hybrid; USD 120,000 - 160,000; Full time

Job summary

Tempus is seeking a Lead Clinical Data Manager to spearhead data management activities for global clinical studies across all development stages. You will oversee eCRF design, database builds, data cleaning, and database locks while coordinating with CROs, Biostatistics, and Clinical Operations.

Strong knowledge of CDISC standards and GCP is essential. The role emphasizes cross-functional leadership, regulatory compliance, and a commitment to data quality, with potential travel as needed and a

Qualifications

• BS/BA in scientific discipline required; MS or equivalent preferred.
• Experience with global studies and outsourced CRO models.
• Expert knowledge of data management processes and EDC systems.
• Familiarity with CDISC SDTM/CDASH and 21 CFR Part 11.

Responsibilities

• Lead data management activities across clinical studies, including eCRF development and database build.
• Collaborate with Biostatistics, Clinical Ops, QA, Drug Safety, and CROs.
• Oversee data management plans, data transfers, and study documentation.
• Support inspection readiness and adherence to GCP.

Skills

Data management

EDC systems

Vendor oversight

CDISC SDTM/CDASH

Cross-functional collaboration

Education

BS/BA in scientific discipline

MS preferred

Tools

Medidata Rave EDC

Microsoft Word

Microsoft Excel

Job description

Tempus is seeking a Lead Clinical Data Manager to spearhead data management activities for global clinical studies across all development stages. You will oversee eCRF design, database builds, data cleaning, and database locks while coordinating with CROs, Biostatistics, and Clinical Operations.

Strong knowledge of CDISC standards and GCP is essential. The role emphasizes cross-functional leadership, regulatory compliance, and a commitment to data quality, with potential travel as needed and a