Remote Global Medical Affairs Leader for Sleep Neuroscience

Eli Lilly and Company; United States; Remote; USD 177,000 - 308,000; Full time

Job summary

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, seeks an Executive Director, Global Medical Affairs to lead the global medical strategy for our orexin program. The role is remote, based in the US, with occasional travel (~20%), reporting to the Head of Medical Affairs.

You will partner across commercial, market access, HEOR, regulatory, and clinical development to drive launch readiness, evidence generation, and external engagement in global markets, ensuring

Qualifications

• Advanced scientific or clinical degree (MD, PharmD, or PhD).
• Minimum 10 years of Medical Affairs leadership with 5 years global experience.
• Experience in neuroscience, sleep medicine, neurology, psychiatry, or rare disease.
• Proven global product launch leadership.
• Experience as global medical lead for late-stage development or commercial products.
• Strong understanding of medical affairs, evidence generation, payer evidence requirements, and commercialization readiness.
• Ability to drive strategy in a matrix environment.
• Proven collaboration with commercial, market access, HEOR, regulatory, and clinical development teams.
• Exceptional communication, presentation, and stakeholder management skills.

Responsibilities

• Lead global medical strategy and tactical plan for cleminorexton.
• Serve as the Global Medical Affairs Lead and core member of the cross-functional asset team.
• Ensure alignment of medical strategy with corporate objectives, milestones, and plans.
• Establish long-range medical affairs planning to support regulatory approvals and lifecycle management.
• Identify scientific opportunities, evidence gaps, and stakeholder needs.

Skills

Global medical leadership

Stakeholder management

Strategic planning

Evidence generation

Scientific communications

Cross-functional collaboration

Education

MD/PhD/PharmD

Job description

Centessa Pharmaceuticals, a wholly owned subsidiary of Eli Lilly and Company, seeks an Executive Director, Global Medical Affairs to lead the global medical strategy for our orexin program. The role is remote, based in the US, with occasional travel (~20%), reporting to the Head of Medical Affairs.

You will partner across commercial, market access, HEOR, regulatory, and clinical development to drive launch readiness, evidence generation, and external engagement in global markets, ensuring