Remote Drug Discovery Scientist: AI Research & Evaluation

Synthires; California; Remote; USD 83,000 - 124,000; Part time

Benefits offered by this job

Fully remote

Hourly contract engagement

Claude Max subscription reimbursed

Job summary

Synthires is seeking experienced Drug Discovery Scientists to design AI-driven research tasks for pharmaceutical R&D. You will craft realistic problems that require reasoning across incomplete and indirect evidence, using source-grounded data rooms and rigorous grading rubrics.

The role emphasizes distinguishing genuine scientific reasoning from pattern matching, with expert evaluation of AI outputs for quality and defensibility in a fully remote setting.

Qualifications

• PhD or equivalent in drug discovery, medicinal chemistry, chemical biology, biochemistry, or related field.
• Strong understanding of drug discovery methodologies and scientific evidence evaluation.
• Ability to construct complex scientific problems with defensible conclusions.
• Strong analytical and critical-thinking skills.
• Experience working in a remote research environment and committing to at least 20 hours per week.

Responsibilities

• Design challenging, realistic drug discovery research problems based on authentic scientific workflows.
• Develop scenarios where correct conclusions come from multiple pieces of evidence rather than direct statements.
• Build data rooms with real, source-grounded scientific data and documentation.
• Ensure every decisive scientific value and evidence can be traced to a reliable source.
• Create grading documents and evaluation rubrics to assess scientific reasoning and conclusions.
• Evaluate AI-generated research outputs for scientific accuracy, logical consistency, and defensibility.
• Run verification and calibration processes for reproducibility and appropriate difficulty.
• Identify weaknesses in task design and revise accordingly.
• Provide expert judgment on scientific questions, task difficulty, and quality of AI reasoning.
• Collaborate with project reviewers and domain experts to refine research tasks.

Skills

Mechanistic enzymology

Structure-guided peptide design

Structure-guided antibody design

Fragment-based drug discovery

Structure-based medicinal chemistry

PhD or equivalent industry experience

Drug discovery methodologies

Scientific writing

Remote research environment

20 hours per week commitment

Education

PhD or equivalent in drug discovery/related field

Job description

Synthires is seeking experienced Drug Discovery Scientists to design AI-driven research tasks for pharmaceutical R&D. You will craft realistic problems that require reasoning across incomplete and indirect evidence, using source-grounded data rooms and rigorous grading rubrics.

The role emphasizes distinguishing genuine scientific reasoning from pattern matching, with expert evaluation of AI outputs for quality and defensibility in a fully remote setting.