Radiopharma Manufacturing Site Leader & VP

AdvanCell; Andover (MA); On-site; USD 293,000 - 358,000; Full time

Job summary

The Site Head & Vice President, Manufacturing at AdvanCell is responsible for the operational leadership, performance, and scalability of the Andover, MA radiopharmaceutical manufacturing operations. This role ensures reliable clinical supply, regulatory compliance, and readiness for future commercialization.

Working with global technical and manufacturing teams, you will translate strategic objectives into scalable capabilities, lead a high-performing site function, and drive continuous

Qualifications

• PhD, MSc, or equivalent degree in engineering, pharmaceutical sciences, or a related field.
• 5+ years of cross-functional leadership in pharmaceutical manufacturing.
• Solid understanding of cGMP requirements for parenteral products (PIC/S, ICH).
• Experience scaling site operations from clinical to commercial.
• Strong leadership, strategy, and stakeholder management.
• Excellent communication and analytical problem-solving skills.
• Commitment to diversity and inclusion in a team setting.

Responsibilities

• Provide operational leadership for site operations, manufacturing performance, and organizational effectiveness at the Andover manufacturing facility.
• Lead the development and execution of site strategy, operating systems, policies, and objectives to support clinical development, commercial readiness, and corporate goals.
• Oversee all site functions, including Manufacturing, Technical Services, Manufacturing Sciences, Facilities, Supply Chain & Logistics, Radiation Safety, Health, Safety & Environment (HSE), and associated support functions.
• Ensure the safe, compliant, and reliable manufacture and supply of Pb-212 radiopharmaceutical products to support clinical trials, pipeline development, and future commercial demand.
• Drive operational excellence through performance management, KPIs, risk management, resource optimization, and continuous improvement initiatives that enhance efficiency, reliability, and process robustness.
• Develop manufacturing capacity, infrastructure, and operational readiness plans to support pipeline growth, technology transfers, scale-up activities, facility expansion, and commercialization.
• Lead clinical supply planning and execution, including production scheduling, isotope availability, inventory management, and distribution logistics to ensure uninterrupted product supply.
• Partner cross-functionally with Quality, Regulatory, R&D, CMC, Clinical, Engineering, and Infrastructure teams to deliver site objectives, technical initiatives, and manufacturing strategies aligned with business priorities.
• Ensure ongoing compliance with cGMP, FDA, NRC and other applicable regulatory requirements, maintaining inspection readiness and serving as the senior site representative during regulatory inspections and audits.
• Foster a strong culture of safety, quality, accountability, and continuous improvement, ensuring adherence to all corporate and site HSE and quality standards.
• Build, lead, and develop a high-performing leadership team and workforce through effective talent management, coaching, succession planning, and organizational development.
• Establish and maintain effective communication, collaboration, and knowledge-sharing practices across the site and broader manufacturing network.
• Contribute to corporate strategy, budgeting, forecasting, and business planning activities to ensure alignment between site operations and organizational objectives.
• Champion the company’s mission, values, and culture, creating an engaged, high-performing workplace that supports innovation, growth, and operational excellence.

Skills

PhD/MSc or equivalent

Cross-functional leadership

Regulatory knowledge

Site scaling experience

Leadership & stakeholder management

Communication skills

Diversity & inclusion

Education

PhD, MSc, or equivalent in engineering/pharmaceutical sciences

Job description

The Site Head & Vice President, Manufacturing at AdvanCell is responsible for the operational leadership, performance, and scalability of the Andover, MA radiopharmaceutical manufacturing operations. This role ensures reliable clinical supply, regulatory compliance, and readiness for future commercialization.

Working with global technical and manufacturing teams, you will translate strategic objectives into scalable capabilities, lead a high-performing site function, and drive continuous