R&D Chemist I/II/III

Bachem Holding AG; Torrance (CA); On-site; USD 65,000 - 89,000; Full time

Benefits offered by this job

Annual bonus

Medical/Dental/Vision coverage

401(k) with employer contribution

Paid vacation and sick days

Job summary

Bachem Americas in Torrance, CA, seeks an R&D Chemist II for the Process Development Group to purify, analyze and isolate GMP-grade peptides. You will perform preparative and analytical RP-HPLC, follow SOPs and BPRs, and work closely with chemists to meet project timelines and quality goals.

Required are a chemistry/biochemistry/bioengineering degree with hands-on GMP lab experience and strong knowledge of GMP/ICH guidelines. Excellent documentation and teamwork are essential.

Qualifications

• Hands-on RP-HPLC and ion exchange chromatography in GMP settings.
• Experience with protein/peptide chemistry in a lab environment.
• Strong GMP and ICH guideline knowledge.
• Proficient data recording and notebook discipline.
• Excellent written and oral communication abilities.

Responsibilities

• Purification, analysis, and isolation of GMP-grade peptides under supervision.
• Operate preparative and analytical HPLC and document conditions in BPR.
• Ensure GMP compliance and follow SOPs for all tasks.
• Collaborate with synthetic chemists to meet timelines and quality targets.
• Maintain safety and housekeeping standards in the lab.

Skills

RP-HPLC

Ion exchange chromatography

GMP knowledge

SOP/BPR familiarity

Data organization

Communication skills

Multitasking

Independent time management

Education

Bachelor's degree in Chemistry/Biochemistry/Bioengineering

Master's degree in Chemistry/Biochemistry/Bioengineering

Tools

RP-HPLC

Ion exchange chromatography

Chromatography platforms

Microsoft Word

Excel

PowerPoint

Job description

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The R&D Chemist II in the Process Development Group will be responsible for purification, analysis, and isolation of GMP grade peptides under GMP regulations. This work will encompass preparative and analytical chromatography, and lyophilization.

What you will do

• Perform preparative and analytical reversed-phase high performance liquid chromatography (HPLC) and isolation operations with direction from supervisor
• Follow written procedures such as Standard Operating Procedures (SOP) and Batch Production Records (BPR)
• Comply with SOP’s in all aspects of the work and follow GMP regulations
• With appropriate training, become well-versed in operation of specific chromatography platforms used in the GMP Manufacturing Group
• Document accurately purification conditions and yields in the Batch Production Records (BPR)
• Work in close cooperation with synthetic chemists to meet project commitments with regard to deliverable timelines, quantity, and quality
• Constantly monitor and improve practices by learning from past projects
• Ensure that all laboratory safety and housekeeping standards are met

Qualifications

• Bachelor's Degree in Chemistry, Biochemistry, or Bioengineering with 3-5 years’ experience Required or
• Master's Degree in Chemistry, Biochemistry, or Bioengineering with 1-3 years’ experience Required
• Hands-on experience in preparative and analytical reversed-phase high performance liquid chromatography (HPLC) and isolation operations in a GMP environment. Required and
• Hands-on laboratory experience (academic acceptable, industry preferred) in protein or peptide chemistry Required and
• Experience in RP-HPLC and ion exchange chromatography Required and
• Experience with synthesis and/or purification Required
• Strong knowledge of GMP regulations and ICH guidelines
• Good laboratory notebook and data organization skills
• Excellent written and oral communication skills
• Basic computer knowledge, including Microsoft Word, Excel and PowerPoint
• Ability to effectively organize, multitask, and work in a fast-paced, deadline driven work environment
• Ability to communicate in a proactive and solution-focused manner, including keeping management aware of potential issues
• Detail oriented with the ability to troubleshoot and resolve problems
• Ability to work independently and manage one’s time
• Communicate effectively and ability to function well in a team environment

Base Annual Salary Range

Chemsit I: $31.07 - $42.72

Placement of new hires in this wage range is based on several factors including education, skill sets, experience, and training.

Total Rewards

We offer all Team Members a total rewards package including competitive pay, annual performance bonus, a generous benefit package with comprehensive Medical/Dental/Vision coverage, 401(k) plan with employer contribution, and paid vacation, personal and sick days.

Corporate Social Responsibility

Bachem takes responsibility for future generations by a careful handling of resources and avoiding environmental risks. We continually improve our ecological performance and develop and implement new approaches for enhancing employees’ environmental awareness. EcoVadis has awarded Bachem Gold Medal status in their assessment of Bachem.

Bachem Americas is an Equal Opportunity Employer

As an equal opportunity employer, we celebrate the diversity of our team and are committed to building an inclusive workplace where individuals are hired and advanced based on merit, skills, and qualifications. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, or other legally protected status.

At Bachem, you’ll find a diverse, multicultural team. The (a)in the job title stands for all. We welcome applications from all candidates. What matters are your skills and motivation—regardless of age, gender, background, religion, or sexual orientation.