QC Chemist

TriSearch; Philadelphia (Philadelphia County); On-site; USD 85,000 - 120,000; Full time

Job summary

TriSearch seeks an Analytical Chemist to join our Quality Control team in Horsham, PA. The role emphasizes analytical testing, method development, method transfer, and stability studies to support pharmaceutical development and manufacturing under cGMP.

The candidate will operate instruments including HPLC/UHPLC, GC, UV/Vis, ICP-MS, and Karl Fischer; review data for accuracy and integrity; and collaborate with cross-functional teams to ensure timely project delivery.

Qualifications

• Bachelor's degree in Chemistry, Chemical Engineering, or similar.
• Minimum of 5 years pharmaceutical analytical lab experience; 10+ years preferred.
• Experience in a cGMP pharmaceutical environment and comfort with regulatory requirements.
• Hands-on experience with HPLC/UHPLC, dissolution testing, and other analytical instrumentation.
• Experience with method development, method validation, and troubleshooting, with data review responsibilities.

Responsibilities

• Perform analytical testing of raw materials, in-process samples, stability samples, and finished products.
• Execute method development, transfer, validation, and troubleshooting activities.
• Operate and maintain analytical instrumentation (HPLC/UHPLC, dissolution, ICP-MS, GC, UV/Vis, Karl Fischer).
• Review data, protocols, and reports for cGMP and regulatory compliance.
• Support stability studies, calibration, and routine lab maintenance.
• Collaborate with cross-functional teams and interact with clients to meet project timelines.

Skills

Analytical testing

Regulatory compliance

Data integrity

Education

Bachelor's degree in Chemistry or related field

Tools

HPLC/UHPLC

Dissolution testing

ICP-MS

UV/Vis Spectrophotometers

Gas Chromatography (GC)

Karl Fischer

Malvern particle size analyzers

LIMS

Electronic Laboratory Notebooks (ELN)

Job description

Analytical Chemist (Quality Control)

Location: Horsham, PA

About The Opportunity

Seeking Analytical Chemist to join a highly respected pharmaceutical CDMO located in the Horsham, Pennsylvania area. This privately held organization has more than three decades of success supporting leading global pharmaceutical companies and is recognized for its exceptional quality standards, strong regulatory history, and investment in advanced laboratory technology. The company offers a collaborative environment where scientists work directly with clients on innovative drug development programs spanning early-stage development through commercial manufacturing.

Position Summary

The Analytical Chemist will play a key role within the Quality Control laboratory, performing analytical testing, method development, method transfer, and stability testing while ensuring compliance with current Good Manufacturing Practices (cGMP) and regulatory requirements. This position is ideal for a technically strong scientist who enjoys solving complex analytical challenges, working with cutting-edge instrumentation, and contributing to the successful development and release of pharmaceutical products.

Key Responsibilities

• Perform analytical testing of raw materials, in-process samples, stability samples, and finished pharmaceutical products.
• Execute method development, method transfer, validation, and analytical troubleshooting activities.
• Operate and maintain analytical instrumentation, including:
• HPLC/UHPLC
• Dissolution systems
• ICP-MS
• UV/Vis Spectrophotometers
• Gas Chromatography (GC)
• Karl Fischer
• Malvern particle size analyzers and other laboratory instrumentation
• Conduct second analyst reviews to ensure data accuracy and integrity.
• Review laboratory documentation, analytical data, protocols, and reports for compliance with cGMP, USP, ICH, and FDA regulations.
• Support stability studies, equipment calibration, and routine laboratory maintenance.
• Collaborate with cross-functional teams and interact with clients to support project timelines.
• Participate in continuous improvement initiatives with a strong focus on prevention, quality by design (QbD), and operational excellence.
• Utilize electronic laboratory systems, including LIMS and electronic laboratory notebooks.

Qualifications

• Bachelor's degree in Chemistry, Chemical Engineering, or similar.
• Minimum of 5 years of pharmaceutical analytical laboratory experience; 10+ years preferred.
• Experience working within a cGMP pharmaceutical laboratory.
• Hands-on experience with HPLC/UHPLC, dissolution testing, and other analytical instrumentation.
• Proven experience with method development, method validation, and analytical troubleshooting.
• Working knowledge of FDA, USP, ICH, and 21 CFR regulatory requirements.
• Experience supporting regulatory inspections, client audits, and second reviewer responsibilities is highly desirable.