Proteomics & Genomics Sample Prep Scientist

Glyphic Biotechnologies; Berkeley (CA); On-site; USD 90,200 - 129,500; Full time

Benefits offered by this job

Employee Stock Option Plan

Employer Retirement Contributions to

Generous Paid Time Off

Paid Maternity and Paternity Leave

Office Snacks and Beverages

Regular Team Bonding Activities

Job summary

Glyphic Biotechnologies is seeking a Scientist of Applications Sample Preparation to optimize and apply sample preparation workflows for its single-molecule proteome sequencing platform (ProSE) and complementary omics workflows. The role requires hands-on execution across proteomics and nucleic acid platforms and collaboration with cross-disciplinary teams in a fast-paced setting.

You will drive protocol optimization, generate sequencing-ready outputs, and contribute to data analysis and

Qualifications

• Degree in biochemistry, chemical biology, molecular biology, or equivalent field with hands-on sample prep experience.
• Experience executing sample prep across proteomics and nucleic acid platforms and generating quantitative readouts.
• Proficiency with NGS library preparation methods and nucleic acid extraction, QC, and amplification.
• Ability to work in high-throughput environments and communicate results clearly across teams.

Responsibilities

• Evaluate and process incoming biological samples for workflows across proteomics and genomics.
• Extract and quantify nucleic acids and proteins from diverse samples.
• Optimize assay performance by varying reagent concentrations, incubation times and conditions.
• Prepare sequencing libraries for DNA-seq, RNA-seq, and ribosome profiling; generate analysis-ready outputs.
• Collaborate with proteomics, chemistry and data science teams to guide project strategy.

Skills

Sample preparation

Molecular biology

NGS library prep

Proteomics

Python/R

Education

PhD / MS / BS with relevant experience

Tools

LC-MS

Illumina sequencing

ONT / PacBio

Job description

Glyphic Biotechnologies is seeking a Scientist of Applications Sample Preparation to optimize and apply sample preparation workflows for its single-molecule proteome sequencing platform (ProSE) and complementary omics workflows. The role requires hands-on execution across proteomics and nucleic acid platforms and collaboration with cross-disciplinary teams in a fast-paced setting.

You will drive protocol optimization, generate sequencing-ready outputs, and contribute to data analysis and