Process Development Senior Scientist

BioSpace; Thousand Oaks (CA); On-site; USD 120,000 - 160,000; Full time

Job summary

Amgen is seeking a Process Development Senior Scientist for the Drug Substance Technologies - Synthetics group in Thousand Oaks, CA, or Cambridge, MA. You will invent synthetic routes and develop robust manufacturing processes for drug substances, with emphasis on synthetic and hybrid assets.

The role requires a PhD (or PharmD/MD in Chemistry) or equivalent experience, strong organic chemistry background, and ability to work in a cross-disciplinary team to deliver regulatory-ready results.

Qualifications

• PhD in organic chemistry with emphasis on synthetic methods and drug substance development.
• Post-doctoral experience in pharma/biotech is a plus.
• Strong track record of publications and presentations.

Responsibilities

• Invent synthetic routes and develop safe, robust, and cost-effective processes for drug substances.
• Advance enabling technologies to accelerate pharmaceutical development and improve sustainability.
• Support cGMP manufacturing and tech transfer to internal and external facilities.
• Ensure process performance through understanding and characterization; contribute to team data interpretation.
• Prepare technical updates and documentation for regulatory filings; collaborate cross-functionally.

Skills

Organic chemistry

Process chemistry

cGMP

Modeling

Education

PhD in Chemistry

PharmD or MD in Chemistry

Master's degree

Bachelor's degree

Job description

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What You Will Do

Lets do this. Lets change the world. In this vital role you will join our Drug Substance Technologies - Synthetics (DSTS) group at either our Thousand Oaks, CA or at our Cambridge, MA campus. Amgens DSTS group within Process Development (PD) is responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development. The successful candidate will be a highly motivated and team-oriented individual with a strong background in organic chemistry with a proven track record of scientific innovation and achievement.

Key Responsibilities

• Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances
• Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency
• Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers
• Ensure process performance through process understanding, modeling and characterization
• Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
• Work cross-functionally to deliver regulatory documents and support regulatory filings
• Serve as a technical expert and keep current in the field of organic and process chemistry
• Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists
• Work independently in advancing projects and studies within required deadlines.

What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. dynamic professional we seek is an individual with these qualifications.

Basic Qualifications

• Doctorate degree PhD OR PharmD OR MD Chemistry completed by August 2026
• OR
• Masters degree and 3 years of Scientific experience
• OR
• Bachelors degree and 5 years of Scientific experience

Preferred Qualifications

• Ph.D. in organic chemistry with a specialization in total synthesis, reaction methodology, mechanistic studies,
• Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
• Track record of peer-reviewed publications and research presentations
• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
• Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects
• A research summary included with CV is strongly encouraged

What You Can Expect Of Us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.