Process Development Senior Scientist

BioSpace; Cambridge (MA); Hybrid; USD 120,000 - 150,000; Full time

Benefits offered by this job

Retirement plan

Medical, dental, vision coverage

Life and disability insurance

Flexible spending accounts

Annual bonus

Stock-based incentives

Time-off plans

Flexible work models

Job summary

Amgen is seeking a Process Development Senior Scientist in the United States to lead invention, development, and implementation of drug substance manufacturing processes for synthetic and hybrid assets. You will design robust, cost-effective processes and advance enabling technologies to shorten development timelines.

You will support regulatory filings, contribute experimental data, and collaborate with chemists, engineers and scientists to ensure process performance and transfer to

Qualifications

• PhD/PharmD/MD is required for advanced roles.
• Masters with 3+ years industry experience considered.
• Bachelors with 5+ years industry experience acceptable.

Responsibilities

• Invent synthetic routes and develop safe, robust processes for drug substances.
• Advance enabling technologies to accelerate pharmaceutical development and improve sustainability.
• Support cGMP manufacturing and tech transfer to internal and contract manufacturers.
• Ensure process performance through understanding, modeling and data interpretation.
• Collaborate with cross-functional teams to deliver regulatory documents and filings.
• Stay current in organic chemistry and related fields as a technical expert.

Education

PhD/PharmD/MD

Masters + 3 years industry experience

Bachelors + 5 years industry experience

Job description

Join Amgens Mission of Serving Patients

At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Process Development Senior Scientist

What you will do

Lets do this. Lets change the world. In this vital role you will be responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.

Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances

Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency

Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers

Ensure process performance through process understanding, modeling and characterization

Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.

Work cross-functionally to deliver regulatory documents and support regulatory filings

Serve as a technical expert and keep current in the field of organic and process chemistry

Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists

Work independently in advancing projects and studies within required deadlines.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is highly motivated with these qualifications.

Basic Qualifications

Doctorate degree PhD OR PharmD OR MD

OR

Masters degree and 3 years of industry experience

OR

Bachelors degree and 5 years of industry experience

Preferred Qualifications

Ph.D. in organic chemistry and/or biochemistry with a specialization in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, and/or conjugation chemistry

Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry

Track record of peer-reviewed publications and research presentations

Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results

Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects

A research summary included with CV is strongly encouraged

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In Addition To The Base Salary, Amgen Offers a Total Rewards Plan, Based On Eligibility, Comprising Of Health And Welfare Plans For Staff And Eligible Dependents, Financial Plans With Opportunities To Save Towards Retirement Or Other Goals, Work/life Balance, And Career Development Opportunities That May Include

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.

We provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.