Process Development Engineer III Upstream

USA - 3316 Takeda Development Center Americas, Inc.; Lexington (MA); On-site; USD 90,000 - 141,000; Full time

Job summary

Takeda Lexington, MA is seeking a Process Development Engineer III to design, optimize, and scale-up cell culture manufacturing processes. You will collaborate with scientists, engineers, and manufacturing teams on technology transfer and development programs from early stage to commercialization.

You will execute experiments, analyze data, and author protocols while maintaining documentation and supporting cross-functional projects in a GMP environment.

Qualifications

• Associate’s degree with 4+ years, Bachelor’s degree with 2+ years, or Master’s degree with 0+ years of relevant industry experience in Chemistry, Biology, Pharmacy, Engineering, or a related scientific discipline.
• Experience in a biologics laboratory or GMP manufacturing environment.
• Experience maintaining and troubleshooting laboratory equipment.
• Ability to follow written procedures, SOPs, and work instructions.
• Experience documenting laboratory work using batch records or notebooks.
• Strong written and verbal communication skills.
• Ability to learn new techniques and manage multiple priorities.
• Knowledge of aseptic technique, solution chemistry, and lab equipment operation (bench-top bioreactors).
• Experience preparing cell culture media and process solutions.
• Preferred: experience supporting technology transfer.
• Cell culture process development experience in biopharma.
• Familiarity with scale-up and process optimization.
• Experience in a cross-functional development organization.

Responsibilities

• Execute process development experiments and unit operations with limited supervision.
• Prepare and author experimental protocols and supporting documentation.
• Contribute to project deliverables across development programs.
• Independently analyze, interpret, and communicate experimental data.
• Identify technical challenges and implement solutions with team collaboration.
• Support design and execution of new experiments and process improvements.
• Author and support technology transfer documentation for internal manufacturing and external partners.
• Collaborate cross-functionally with scientists, engineers, and manufacturing teams.
• Maintain laboratory facilities, equipment, and documentation per procedures.
• Present project updates and experimental results to teams and leadership.
• Apply biological and engineering principles to solve process development challenges.

Skills

Process development

Cell culture

GMP manufacturing

SOPs

Education

Bachelor’s degree

Associate’s degree

Master’s degree

Tools

Bench-top bioreactors

Job description

About the role As a Process Development Engineer III, you will work primarily with scientists and engineers in the process development team to design, optimize, and scale-up cell culture manufacturing processes. You will support process development activities, technology transfer to internal manufacturing sites and CMOs, and contribute to technology innovation initiatives. You will independently execute routine and complex laboratory experiments, support process characterization and scale-up activities, analyze data, and contribute to technical documentation. Through collaboration with cross-functional teams, you will help advance process development programs from early-stage development through technology transfer and commercialization.

How you will contribute

• Execute process development experiments and unit operations with limited supervision.
• Prepare and author experimental protocols and supporting documentation.
• Contribute significantly to project deliverables across one or more development programs.
• Independently analyze, interpret, and communicate experimental data.
• Identify technical challenges related to cell culture process development and implement solutions in collaboration with team members.
• Support the design and execution of new experiments, applications, and process improvements.
• Author and support technology transfer documentation for internal manufacturing and external partners.
• Collaborate cross-functionally with scientists, engineers, manufacturing teams, and other stakeholders.
• Maintain laboratory facilities, equipment, and documentation in accordance with applicable procedures and quality requirements.
• Present project updates, technical challenges, and experimental results to team and departmental audiences.
• Apply fundamental biological and engineering principles to solve practical process development challenges.

What you bring to Takeda

• Associate’s degree with 4+ years, Bachelor’s degree with 2+ years, or Master’s degree with 0+ years of relevant industry experience in Chemistry, Biology, Pharmacy, Engineering, or a related scientific discipline.
• Previous experience in a biologics laboratory or GMP manufacturing environment.
• Experience maintaining and troubleshooting laboratory equipment.
• Demonstrated ability to follow written procedures, SOPs, and work instructions.
• Experience documenting laboratory work using batch records, laboratory notebooks, or other controlled documentation systems.
• Strong written and verbal communication skills.
• Ability to learn new techniques and manage multiple priorities effectively.
• Knowledge of aseptic technique, solution chemistry, and laboratory equipment operation, including bench‑top bioreactors.
• Experience preparing cell culture media and process solutions.
• Preferred: Experience supporting technology transfer activities.
• Cell culture process development experience in a biopharmaceutical environment.
• Familiarity with scale‑up and process optimization activities.
• Experience working in a cross‑functional development organization.

Takeda Compensation and Benefits Summary

For location: Lexington, MA U.S. Base Salary Range: $89,900.00 - $141,240.00 The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

Locations

Lexington, MA

Worker Type

Employee Worker Sub-Type Regular Time Type Full time Job Exempt Yes

Disclaimer

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Company Overview

Takeda is an industry‑leading, global pharmaceutical company with an unwavering dedication to putting patients at the center of everything we do. We live our values of Takeda‑ism – Integrity, Fairness, Honesty, and Perseverance – and are united by our mission to strive towards Better Health and a Brighter Future for people worldwide through leading innovation in medicine. Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. At Takeda, you will make an impact on people’s lives – including your own. Takeda is an equal opportunity employer.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.