Process Development Engineer III, Analytical Science: Synthetic and Bioconjugation Scale-Up Technologies (SBST)

Regeneron Pharmaceuticals; Village of Tarrytown (NY); On-site; USD 110,000 - 179,000; Full time

Benefits offered by this job

Student Loan Paydown program

Tuition Reimbursement

Family Care Benefits

Relocation Assistance

Inclusion, Culture and Well-Being

Job summary

Regeneron Pharmaceuticals in Tarrytown, NY seeks a Process Development Engineer III to join the PMPD SBST Analytics group on-site. You will lead analytical method development, transfer, and troubleshooting to advance bioconjugate programs from development toward commercialization.

The role requires strong communication, collaboration with internal teams and CDMOs, and hands-on leadership in a fast-paced environment while ensuring compliance and data integrity.

Qualifications

• B.S./M.S./Ph.D. with relevant chemistry or biology background
• Hands-on analytical method development for bioconjugates, antibodies, or small molecules
• Experience transferring methods to internal/external labs and troubleshooting
• Analytical leadership for bioconjugate programs
• Strong written and verbal communication; data presentation to diverse audiences
• Experience drafting analytical methods and regulatory reports

Responsibilities

• Design and execute analytical testing, method development, and characterization for bioconjugate process development
• Lead analytical deliverables: method development, transfer, training, and troubleshooting
• Communicate complex results clearly to technical and non-technical audiences
• Author procedures and reports to support program timelines
• Improve workflows, data digitization, and sample management
• Maintain lab safety and compliance
• Scout and implement new high-throughput analytics technologies
• Mentor peers and junior team members

Skills

Analytical method development

Method transfer

Troubleshooting

Communication

Drafting methods/reports

Cross-functional collaboration

Initiative / learning agility

Education

Bachelor's in chemistry/biochemistry/biology/chemical engineering

MS or PhD with relevant experience

Tools

Empower

ELN (electronic lab notebook)

Job description

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer III to join our Preclinical Manufacturing & Process Development (PMPD) organization’s Synthetic and Bioconjugation Scale-up Technologies (SBST) Analytics group, on-site in Tarrytown, NY. In this role, you will serve as the analytical lead to develop fit-for-purpose analytical methods, transfer methods, and provide troubleshooting support to advance a diverse bioconjugate pipeline.

This position offers the opportunity to lead and implement analytical deliverables, working closely with bioconjugation teams and internal/external collaborators (CDMOs) to advance bioconjugate programs from development to commercialization.

When & where:

• Shift Requirements: Full-time, standard business hours
• Location: On-site in Tarrytown, NY
• Flexibility & travel: Minimal to no travel; on-site presence required to support lab operations and collaboration with internal/external CDMO partners

What you’ll do:

• Independently design and execute analytical testing, method development, and characterization to enable bioconjugate process development
• Serve as the subject matter expert to lead and design analytical deliverables: robust method development, method transfer to internal/external receiving labs, training, and troubleshooting to move programs forward
• Connect, interpret, and communicate complex results into clear, actionable next steps for technical and non-technical audiences to drive timely decisions
• Author high-quality documentation (e.g., procedures, development and characterization reports, ELN entries) in a timely manner to support program timelines
• Drive, build, and improve business workflows: documentation standardization, data digitization, and sample management
• Maintain compliance with lab and environmental safety requirements and promote a safe lab environment
• Proactively scout, evaluate, and implement new or improved technologies for high-throughput analytics and real-time decision-making
• Lead equipment upkeep and troubleshooting, maintain an organized workspace, and proactively plan for lab resources
• Mentor and support peers and junior team members (direct and/or indirect via matrix)

The environment and physical rhythms of this role:

• This is a hands-on, on-site laboratory role serving as analytical lead across bioconjugate programs, requiring close collaboration with internal teams and external CDMO partners and comfort navigating complex, ambiguous problems.
• Flexibility to thrive in a fast-paced, highly collaborative environment while independently driving projects forward is required.

Let’s find out if we’re a fit:

Must-haves:

• B.S. with 10+ years of relevant experience, M.S. with 7+ years, or recent Ph.D. with 0-3 years of relevant experience in chemistry, biochemistry, biology, chemical engineering, or a related field
• Hands-on experience with analytical method development for antibody, bioconjugate, and/or synthetic molecules (e.g., small molecule, PEG, peptides, and/or siRNA), such as electrophoresis, HPLCs, LC-MS, UV spectroscopy, plus associated software (e.g., Empower)
• Hands-on experience transferring methods to internal/external labs, and troubleshooting
• Demonstrated experience serving as an analytical lead for bioconjugate programs, collaborating effectively with internal teams and external CDMOs
• Strong written and verbal communication skills, including the ability to present data clearly to diverse audiences
• Experience drafting analytical methods, development, and characterization reports to support regulatory filing
• Ability to work independently and collaboratively across cross-functional teams to persuade and drive data-based decisions
• Demonstrated initiative, learning agility, and a growth mindset in a fast-paced environment

Preferred / nice-to-haves:

• Customer-centric mindset in providing analytical support across different phases of drug development
• Experience simplifying complex technical messages for varied audiences

Thrive today. Grow tomorrow.

• Student Loan Paydown program & Tuition Reimbursement
• Family Care Benefits
• Relocation Assistance
• Inclusion, Culture and Well-Being programs (including physical & mental health)

#pmpd

Does this sound like you? We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$109,900.00 - $179,300.00