Principal Statistician

Medtronic plc; Minneapolis (MN); On-site; USD 146,000 - 220,000; Full time

Job summary

Medtronic plc in Minneapolis, MN, is seeking a Principal Statistician – MCRS to design, analyze, interpret, and report clinical data across study phases. You will partner with cross-functional teams to develop statistical approaches for investigations and support regulatory submissions.

The role requires up to 10% travel (domestic and occasional international) and a strong background in biostatistics, SAS/R, and clinical trial design.

Qualifications

• Bachelor’s degree and 7+ years of statistical experience in clinical trial design and/or data analysis.
• Experience with survival analysis, regression modeling, Bayesian methods, adaptive trial designs, group sequential methods, longitudinal analysis
• Experience with GCP/regulatory guidelines for clinical trials and medical devices (ISO, MDR)
• Strong ability to communicate technical content to non-statisticians (written and verbal)
• Experience writing or updating clinical reports/documents.

Responsibilities

• Designs, plans and executes biostatistical components of plans for research and development projects that establish safety, efficacy, and marketability of products.
• Uses sound statistical methodology to conduct studies relating to the life cycle of the product.
• Prepares the statistical component of protocols meeting project objectives and guidelines.
• Develops and applies statistical theories, methods, and software.
• Summarizes and interprets data into tabular/graphic formats for statistical inference and reports.

Skills

Biostatistics

Clinical trials

Statistical analysis

Survival analysis

Bayesian methods

Communication of technical content

Education

Bachelor’s degree in Biostatistics/Statistics

Master’s or PhD in Biostatistics/Statistics

Tools

SAS

R

Statistical programming

Job description

We anticipate the application window for this opening will close on - 20 Nov 2026

Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.

A Day in the Life

Medtronic Clinical Research Solutions (MCRS) provides end-to-end clinical and scientific support services across Medtronic, enabling the execution of clinical studies and delivery of clinical statistical services that support evidence generation throughout the product lifecycle. This team partners with clinical, regulatory, data management, and statistical programming functions to generate high-quality clinical evidence that informs product development and regulatory submissions.

At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. In-person exchanges are invaluable to our work. We’re working a minimum of 4 days a week onsite as part of our commitment to fostering a culture of professional growth and cross-functional collaboration as we work together to engineer the extraordinary.

This position requires up to 10% travel, primarily domestic with occasional international travel.

The Principal Statistician - MCRS supports clinical research studies through statistical design, analysis, interpretation, and reporting of clinical data. This role partners with cross-functional teams to develop statistical approaches for clinical investigations, contribute to study planning and execution, and deliver analyses that support product development and regulatory objectives.

Responsibilities may include the following and other duties may be assigned.

• Designs, plans and executes biostatistical components of plans for research and development projects that establish the conditions essential for determining safety, efficacy, and marketability of pharmaceutical and/or biological products.
• Uses sound statistical methodology to conduct studies relating to the life cycle of the product.
• In development-phase projects, prepares the statistical component of protocols which meet project objectives, health authority guidelines, and clinical trial methodology standards.
• Develops and/or applies statistical theories, methods, and software.
• Summarizes and interprets data into tabular and graphical formats amenable to principles of statistical inference and is responsible for the statistical component of reports describing studies, outcomes and methods used.
• Provides specifications and directions to the clinicians/statistical programmers.
• Supports the regulatory review and approval of the experimental therapies.
• May partner in trial design and in establishing standards for clinical conduct, and the collection, management and/or reporting of data.

Minimum Requirements

• Bachelor’s degree and 7+ years of statistical experience in clinical trial design and/or data analysis within healthcare (or advanced degree with 5+ years)

Nice to Have

• Bachelor's Master’s, or PhD degree in Biostatistics or Statistics
• 7+ years of statistics experience in the medical device industry, pharmaceutical industries, or clinical research organizations (CROs)
• Experience as a biostatistician in clinical studies from the design through approval stages in the medical device or pharmaceutical industries
• Strong applied statistical skills, including survival analysis, regression modeling, Bayesian methods, adaptive trial designs, group sequential methods, longitudinal analysis (including mixed models), interim analysis, missing data strategies and multiple testing strategies
• Advanced knowledge of and/or experience with statistical programming packages, including SAS, R, or another statistical analysis package
• Participation in FDA regulatory meetings, especially panel preparation and presentation
• Experience in Good Clinical Practice (GCP) and/or regulatory compliance guidelines for clinical trials and medical devices (e.g., ISO, MDD/MDR)
• High level of knowledge of clinical trial methods and execution
• High degree of expertise regarding research data management
• High level of competency in Windows environment and with Microsoft Office Tools (Word, Excel)
• Demonstrated ability to communicate technical content to non-statisticians (written and verbal)
• Experience writing or updating clinical reports/documents

For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.

Physical Job Requirements

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position.

The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.

U.S. Work Authorization & Sponsorship

At Medtronic, we are committed to fostering an environment where employees can thrive and make a meaningful impact. In alignment with our enterprise-wide workforce planning approach, U.S. work authorization sponsorship (H-1B, TN, J, etc.) is offered exclusively for Principal-level roles and above, where specialized expertise aligns with long-term business needs. Roles below the Principal level require candidates to possess unrestricted U.S. work authorization at the time of hire and for the duration of employment.

Benefits & Compensation

Medtronic offers a competitive Salary and flexible Benefits Package
A commitment to our employees lives at the core of our values. We recognize their contributions. They share in the success they help to create. We offer a wide range of benefits, resources, and competitive compensation plans designed to support you at every career and life stage.

Salary ranges for U.S (excl. PR) locations (USD):$146,400.00 - $219,600.00

This position is eligible for a short-term incentive called the Medtronic Incentive Plan (MIP).

The base salary range is applicable across the United States, excluding Puerto Rico and specific locations in California. The offered rate complies with federal and local regulations and may vary based on factors such as experience, certification/education, market conditions, and location. Compensation and benefits information pertains solely to candidates hired within the United States (local market compensation and benefits will apply for others).

The following benefits and additional compensation are available to those regular employees who work 20+ hours per week: Health, Dental and vision insurance, Health Savings Account, Healthcare Flexible Spending Account, Life insurance, Long-term disability leave, Dependent daycare spending account, Tuition assistance/reimbursement, and Simple Steps (global well-being program).

The following benefits and additional compensation are available to all regular employees: Incentive plans, 401(k) plan plus employer contribution and match, Short-term disability, Paid time off, Paid holidays, Employee Stock Purchase Plan, Employee Assistance Program, Non-qualified Retirement Plan Supplement (subject to IRS earning minimums), and Capital Accumulation Plan (available to Vice Presidents and above, or subject to IRS earning minimums).

Regular employees are those who are not temporary, such as interns. Temporary employees are eligible for paid sick time, as required under applicable state law, and the Employee Stock Purchase Plan. Please note some of the above benefits may not apply to workers in Puerto Rico.

Further details are available at the link below:

Medtronic benefits and compensation plans

It is the policy of Medtronic to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, Medtronic will provide reasonable accommodations for qualified individuals with disabilities.

If you are applying to perform work for Medtronic, Inc. (“Medtronic”) in any position which will involve performing at least two (2) hours of work on average each week within the unincorporated areas of Los Angeles County, you can find here a list of all material job duties of the specific job position which Medtronic reasonably believes that criminal history may have a direct, adverse and negative relationship potentially resulting in the withdrawal of a conditional offer of employment. Medtronic will consider for employment qualified job applicants with arrest or conviction records in accordance with the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.