Principal stat programmer

Syneos Health, Inc.; Indianapolis (IN); Remote; USD 80,000 - 100,000; Full time

Job summary

A leading biopharmaceutical solutions organization is seeking a Statistical Programmer to develop custom programming code using SAS. Responsibilities include validation programming, maintaining project documentation, and mentoring junior programmers. The ideal candidate will have an undergraduate degree in a scientific or statistical discipline and extensive programming experience, preferably in clinical trials. This position may require minimal travel and offers a dynamic work environment.

Qualifications

• Extensive programming experience in SAS or similar software, ideally in clinical trials.
• Knowledge of CDISC Standards for regulatory requirements.
• Excellent written and verbal communication skills.

Responsibilities

• Develop custom programming code to generate summary tables and datasets.
• Perform validation programming and resolve discrepancies.
• Maintain organized project documentation and ensure inspection readiness.

Skills

SAS programming

Statistical analysis

Communication skills

Mentoring

Education

Undergraduate degree in a scientific or statistical discipline

Tools

SAS

Job description

Updated: September 29, 2025
Location: IND-Remote
Job ID: 25101956

Syneos Health is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities.

Our Clinical Development model brings the customer and the patient to the center of everything that we do. We are continuously looking for ways to simplify and streamline our work to not only make Syneos Health easier to work with, but to make us easier to work for.

Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you’ll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to accelerate the delivery of therapies, because we are passionate to change lives.

Discover what our 29,000 employees, across 110 countries already know: WORK HERE MATTERS EVERYWHERE

Why Syneos Health

• We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
• We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
• We are continuously building the company we all want to work for and our customers want to work with. Because when we bring together diversity of thoughts, backgrounds, cultures, and perspectives – we’re able to create a place where everyone feels like they belong.

Job Responsibilities

• Uses SAS, or other software, to develop custom programming code to generate summary tables, data listings, graphs and derived datasets as specified in the statistical analysis plan and programming specifications.
• Performs validation programming and works with other programmers, biostatisticians, and other project team members to resolve discrepancies or any findings.
• Follow applicable SOPs, WIs, and relevant regulatory guidelines (e.g. ICH).
• Maintains well organized, complete, and up-to-date project documentation, testing, and verification/quality control documents and programs ensuring inspection readiness.
• Manages scheduling and time constraints across multiple projects at a time, sets goals based on priorities from management, and adapts to timeline or priority changes by reorganizing daily workload.
• Develops specifications for datasets and outputs of any complexity according to statistical or sponsor requirements.
• Conducts effective internal meetings and distributes relevant information in advance.
• Displays willingness to work with others and assist with projects and initiatives as necessary to meet the needs of the business.
• Accountable for on-time delivery across concurrent programming deliverables.
• Acts as the lead statistical programmer and directs the programming activities of other programming personnel.
• Reviews project documentation and provides feedback to the appropriate project team members.
• Participates in sponsor meetings, kickoff meetings, and bid defense meetings as statistical programming representative.
• Contributes to the mentoring of programming personnel through developing training courses, presenting training materials, reviewing work, and providing feedback.
• Maintains a good working knowledge of clinical drug development, industry standards, and electronic submission requirements.
• Works cooperatively with other biostatistics and statistical programming personnel to establish standard operation procedures (SOPs), guidelines, policies, and/or procedures.
• Contributes technical expertise to the development of programming tools and macros for standardization and efficiency.
• Performs other work-related duties as assigned.
• Minimal travel may be required

Qualifications

• Undergraduate degree, preferably in a scientific or statistical discipline; in lieu of degree, an equivalent combination of education and demonstrated programming experience.
• Extensive programming experience in SAS or other required software, preferably in a clinical trial environment.
• Knowledge and experience in the use of CDISC Standards for regulatory agency requirements.
• Experience in mentoring others in clinical trial process and CDISC Standards.
• Excellent written and verbal communication skills.
• Ability to read, write, speak and understand English.

Syneos Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, marital status, ethnicity, national origin, sex, gender, gender identity, sexual orientation, protected veteran status, disability or any other legally protected status and will not be discriminated against.