Principal Scientist, Product Development

Veracyte, Inc.; South San Francisco (CA); On-site; USD 170,000 - 190,000; Full time

Job summary

A global genomic diagnostics company is seeking a Principal Scientist in Product Development to drive assay development for high-throughput operations. This role requires a Ph.D. and extensive laboratory experience, with responsibilities including experimental design and collaborating across teams. Veracyte is dedicated to enhancing cancer care through innovative diagnostic advancements and offers compelling career growth opportunities.

Benefits

Competitive compensation and benefits

Opportunities for career growth

Inclusive workplace environment

Qualifications

• Extensive bench experience (>8 years).
• Experience in product development under Design Control.
• Strong background in assay development using molecular genomic technologies.

Responsibilities

• Lead assay development for high-throughput operations.
• Independently design lab workflows and write SOPs.
• Transfer developed assays into production.

Skills

Molecular assay expertise

Bioinformatics knowledge

Experimental design

Team collaboration

Problem-solving skills

Communication skills

Education

Ph.D. in biology, molecular biology, genetics or related field

Job description

Principal Scientist, Product Development

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Principal Scientist, Product Development

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At Veracyte, we offer exciting career opportunities for those interested in joining a pioneering team that is committed to transforming cancer care for patients across the globe. Working at Veracyte – whether it be in one of our labs, corporate offices, the field – enables our employees to not only make a meaningful impact on the lives of patients, but to also learn and grow within a results-driven environment that values innovation, collaboration, and compassion.

The Position

We are looking for a highly motivated individual to join the Product Development team for the position of Principal Scientist. The position is an individual contributor position within the Product Development team, leading a small team of scientist and/or RA, focused on assay development for high-throughput operation, contributing to Veracyte’s novel diagnostic products. This position will significantly contribute to study design and documentation, execute bench studies while working to strict design control requirements.

Responsibilities

• Fluent at conception of novel ideas, developing fully interpretable and actionable experimental designs suitable for high-throughput laboratory.
• Have basic bioinformatics knowledge on molecular data to enable data interpretation and appropriate study design.
• Independently design lab workflow appropriate for the implementation in clinical operations, writing SOPs and experimental protocols, and prepare reports that become part of the Design History File and meet FDA-level requirements.
• Develop assays by taking operational implementation into consideration, including automation, QC and LIMS.
• Transfer developed assays from R&D into production, including training and teaching of CLIA laboratory operators.
• Proven success leading projects collaboratively as both intellectually and as a direct contributor at the lab bench, with delivery of results in a timely fashion and partnering with colleagues and across company disciplines.
• Demonstrate effective mentoring of laboratory tasks performed in the hands of others. Contribute collaboratively on the laboratory troubleshooting needs within and outside of R&D.
• Theoretical and hands-on knowledge of the basic biological principles governing molecular biology, genetics, and biochemistry underlying laboratory assays and clinically relevant information.
• Fluency with clinical sample preparation, assay, and quality control under high-throughput production conditions at the highest standards of traceability and referential integrity.
• Goal-oriented and timeline-driven in support of company objectives in serving patients. Demonstrated ability to thrive in a fast-moving environment and acknowledge that product timeliness is essential to commercial success.
• Interact seamlessly with multi-disciplinary teams such as automation, laboratory infrastructure (e.g. LIMS), clinical, bioinformatics / data analysis, regulatory and marketing groups.
  
  

Who You Are

• Familiarity with design controls and phase-gate processes in product development, translating that into the insight for experimental design through prioritizing must have over nice to have.
• Extensive bench experience (>8 years) is essential. Must have a willingness to participate directly in routine laboratory activities independently and in cooperation/coordination with others. Must be able to lead others and effectively manage (design, monitor, complete, troubleshoot) laboratory project tasks performed in the hands of others.
• Molecular assay expert. Deep theoretical and hands-on knowledge of the biochemistry underlying multi-component molecular biology methods at the sample preparation and assay level. A track record of successfully troubleshooting and optimizing molecular biology techniques/assays in a developed workflow.
• A strong sense of urgency, independent, goal-oriented and timeline-driven.
• Exceptional written and oral communication skills. Able to explain difficult concepts and influence others.
• Proven ability to keep abreast of technological platform advancements and assess their value to the product success and company’s endeavors.
• Excellent problem-solving skills; demonstrated strength intact and diplomacy working with external and internal collaborators.
• Flexibility and open-mindedness in the face of shifting resources & priorities
• Willingness to speak up for their interpretations of data or strategy, to ask questions, or to advocate.
• Experience and comfort working effectively within both a direct and dotted-line management structure.
  
  

Requirements

• Education: D. in biology, molecular biology, genetics or a related field. Domain expertise in cancer is desirable.
• Minimum 8 years of postgraduate laboratory bench experience, with >5 years of industry experience in product development. Relevant industry experience under Design Control and associated Quality Systems in regulated product development (LDT / diagnostics, PMxA or 510(k) device, CE-mark, IVD) strongly preferred.
• Strong background in assay development using molecular genomic technologies (both RNA and DNA), including experience in next-generation sequencing platforms.
• NGS-based genomic data analysis and interpretation/visualization skills.
  
  

The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc. Base pay is one part of the Total Package that is provided to compensate and recognize employees for their work, and this role may be eligible for additional discretionary bonuses/incentives, and restricted stock units. Veracyte is a multi-state employer, and this salary range may not reflect positions that work in other states.

Pay range

$170,000—$190,000 USD

What We Can Offer You

Veracyte is a growing company that offers significant career opportunities if you are curious, driven, patient-oriented and aspire to help us build a great company. We offer competitive compensation and benefits, and are committed to fostering an inclusive workforce, where diverse backgrounds are represented, engaged, and empowered to drive innovative ideas and decisions. We are thrilled to be recognized as a 2024 Certified Great Place to Work in both the US and Israel - a testament to our dynamic, inclusive, and inspiring workplace where passion meets purpose.

About Veracyte

Veracyte (Nasdaq: VCYT) is a global genomic diagnostics company that improves patient care by providing answers to clinical questions, informing diagnosis and treatment decisions throughout the patient journey in cancer and other diseases. The company’s growing menu of genomic tests leverage advances in genomic science and technology, enabling patients to avoid risky, costly diagnostic procedures and quicken time to appropriate treatment. The company’s tests in lung cancer, prostate cancer, breast cancer, thyroid cancer, bladder cancer and idiopathic pulmonary fibrosis are available to patients and its lymphoma subtyping and renal cancer tests are in development. With Veracyte’s exclusive global license to a best-in-class diagnostics instrument platform, the company is positioned to deliver its tests to patients worldwide. Veracyte is based in South San Francisco, California. For more information, please visit www.veracyte.com and follow the company on X (Formerly Twitter).

Veracyte, Inc. is an Equal Opportunity Employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability status. Veracyte participates in E-Verify in the United States. View our CCPA Disclosure Notice.

If you receive any suspicious alerts or communications through LinkedIn or other online job sites for any position at Veracyte, please exercise caution and promptly report any concerns to [e-mail]

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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