Principal Scientist, Peptide Therapeutics — Lab Leader

Genentech; South San Francisco (CA); On-site; USD 143,200 - 265,900; Full time

Benefits offered by this job

Relocation benefits

Annual bonus potential

Comprehensive benefits

Job summary

A leading biotechnology firm in California is seeking a Principal Scientist, Medicinal Chemist to lead efforts in peptide therapeutics. This lab-based role requires a Ph.D. in Organic or Medicinal Chemistry along with expertise in peptide synthesis and computational modeling. You will drive research and mentor junior scientists while overseeing the synthesis and optimization of drug candidates. The expected salary range for this position is $143,200 to $265,900, with potential for a discretionary annual bonus and comprehensive benefits.

Qualifications

• 3+ years of relevant postdoctoral or industry experience.
• Expertise in SPPS and complex organic synthesis.
• Knowledge of macrocyclic peptides and various routes of administration.

Responsibilities

• Drive synthesis of peptides and non-commercial building blocks.
• Optimize potency and drug-like properties through strategic design.
• Lead and mentor project teams in peptide therapeutics.

Skills

Synthetic Execution

Computational Modeling

Collaborative Leadership

Analytical Skills

Education

Ph.D. in Organic or Medicinal Chemistry

Tools

Schrödinger

MOE

Maestro

Job description

A leading biotechnology firm in California is seeking a Principal Scientist, Medicinal Chemist to lead efforts in peptide therapeutics. This lab-based role requires a Ph.D. in Organic or Medicinal Chemistry along with expertise in peptide synthesis and computational modeling. You will drive research and mentor junior scientists while overseeing the synthesis and optimization of drug candidates. The expected salary range for this position is $143,200 to $265,900, with potential for a discretionary annual bonus and comprehensive benefits.