Principal Scientist - In Vitro Immunotherapy

Millipore Corporation; Billerica (MA); On-site; USD 127,000 - 215,000; Full time

Benefits offered by this job

Health insurance

Paid time off (PTO)

Retirement contributions

Job summary

EMD Serono seeks an experienced immunologist to help shape next-generation cancer immunotherapies. You will drive early drug discovery with human immune and tumor cell assays, build translational models, and guide cross-functional teams to IND-enabling decisions.

The role requires strong T-cell biology expertise, leadership in cross-functional settings, and a track record of impactful contributions in immunology or oncology research.

Qualifications

• Bachelor's degree with 8+ years of immunology/immuno-oncology experience in academia or industry.
• Master's degree with 5+ years hands-on immunology/immuno-oncology work.
• PhD with 2+ years post-PhD hands-on immunology/immuno-oncology experience.

Responsibilities

• Shape next-gen cancer immunotherapies and contribute to project ideas.
• Design and oversee in vitro/ex vivo pharmacology studies with immune/tumor cells.
• Build human immunology models to de-risk candidates and translationally inform decisions.
• Scout and implement new assay platforms to improve data quality and throughput.
• Generate in vitro data for target selection and IND-enabling programs.
• Present results to multidisciplinary teams and manage CRO/academic collaborations.

Skills

Immunology

Immuno-oncology

T-cell biology

Cross-functional collaboration

Education

Bachelor's degree with 8+ years experience

Master's degree in Immunology or related field

PhD in Immunology or Oncology

Job description

Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

Help to shape next generation cancer immunotherapies at EMD Serono.

Key Responsibilities:

• Provide creative, strategic input-conceive new project ideas and help design execution-ready workplans
• Drive early drug discovery projects in immuno-oncology by designing, conducting and overseeing in vitro/ex vivo pharmacology studies (human immune cell / tumor cell co-culture assays; profile function via flow cytometry, cytokine/biomarker readouts, and high-content imaging) to support development of novel biological and small molecule agents
• Build and validate human immunology models that complement animal studies to improve translational predictivity and de-risk candidates
• Scout, implement, and champion new assay platforms to investigate novel MOAs, boost data quality, throughput, and decision-making speed
• Independently generate in vitro data for target selection, lead optimization, candidate nomination; and enable program decisions toward IND-enabling studies
• Analyze, document, and present results to multidisciplinary teams and senior leadership; manage studies at CROs and academic collaborations where needed

Who You Are

Minimum Qualifications

• Bachelor's degree with 8+ years of experience, or Master's degree in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 5+ years of hands-on immunology/immuno-oncology (T-cell biology) experience in academia or industry setting ORPhD in Immunology, Cancer Immunology, Oncology, Molecular/Cell Biology, or other Science field with 2+ years post-PhD of hands-on immunology/immuno-oncology (T-cell biology) experience in academia or industry setting.

Preferred Qualifications

• Experience with driving early drug discovery projects and leading cross-functional teams
• Expertise developing, running complex T-cell functional assays (activation receptors, costimulatory molecules, checkpoint receptors) and interpreting mechanistic data to inform early development
• Experience in designing, executing, and interpreting in vitro assays for drug discovery, including tumor models and pharmacology experiments
• Clear, crisp communicator; highly organized multi-tasker who adapts quickly to deliver on-time data packages
• Confident influencer who engages senior leadership and thrives in a matrixed organization
• Proven scientific impact-publications and contributions advancing new therapeutic concepts

Pay Range for this position

$126,900 - $215,400

Benefits offered by the Company

• Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites.

Direct link to benefits site if the hyperlink no longer works: https://careers.emdgroup.com/us/en/benefits].

Our Culture

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!