Principal Scientist II/Senior Principal Scientist, Radioligand Dosimetrist

Novartis Group Companies; Cambridge (MA); Hybrid; USD 119,000 - 223,000; Full time

Job summary

Join a forward-thinking company as a dosimetrist, where your expertise in dosimetry and modeling will drive drug discovery and development. Collaborate in a dynamic, multi-disciplinary environment, contributing to innovative projects that span various phases of clinical trials. This role offers the chance to make a significant impact by integrating advanced dosimetry principles and communicating results to diverse teams. With opportunities for growth and a commitment to diversity and inclusion, this position is ideal for those eager to excel in the field of biomedical research.

Qualifications

• Ph.D. with 3+ years for Principal Scientist II or 5+ years for Senior Principal Scientist.
• Certification as medical dosimetrist required.

Responsibilities

• Build and apply dosimetry workflow for Radioligand Therapy clinical trials.
• Provide solutions to dosimetry-related issues for clinical study teams.

Skills

Algorithms

Data Engineering

Innovation

Mentorship

Modeling And Simulation

Simulation Software

Waterfall Model

Education

Ph.D. in Nuclear Medicine or related field

Tools

MIRD-based dosimetry software

Voxel-based dosimetry software

Job description

Job Description Summary

#LI-Hybrid

About the role:

We are seeking an experienced dosimetrist eager to accelerate drug discovery & development by facilitating rigorous decision making with dosimetry, dosimetry analysis, and modeling & simulation. You will work in a multi-disciplinary environment with opportunities to engage in projects that span a range of phases of drug discovery and development.

This role reports to a PK Sciences Translational Modeling team lead, in a group situated within Biomedical Research, the research engine of Novartis.

Job Description

Key Responsibilities:

• Build and apply dosimetry workflow during planning, then conduct of Radioligand Therapy (RLT) clinical trials, working collaboratively with PKS subteam and cross-functional team
• Provide solutions to dosimetry-related issues to clinical study teams
• Develop and file reports of translational and clinical dosimetry data
• Drive integration of state-of-the-art principles of dosimetry in collaboration with modelers and PK scientists.
• Contribute to retrospective analyses of imaging, dosimetry, safety, and efficacy data in cross-functional analytical teams.
• Proactively seek opportunities to increase the impact and awareness of the Modeling & Simulation group and the RLT platform through communications with internal and external audiences.
• Contribute to group strategy and serve as a modeling & simulation & dosimetry subject area expert across PK Sciences and Biomedical Research and Development initiatives.

Essential Requirements:

• Ph.D. in Nuclear Medicine, Nuclear Physics, Medical Imaging, Medical Physics Radiophysics, or a related field with 3+ (Principal Scientist II) or 5+ (Senior Principal Scientist) years of relevant experience.
• Certification as medical dosimetrist
• Expertise in radiopharmaceutical/internal dosimetry using MIRD-based and voxel-based dosimetry software
• Demonstrated ability to communicate dosimetry and/or modeling results to a multidisciplinary audience to facilitate decision-making.

This is a dual level posting. The final level and title of the offer role would be determined by the hiring team based on the skills, experience & capabilities required to perform the role at the level the role has been offered.

Commitment to Diversity and Inclusion / EEO: The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between $119,700 to $222,300/year for Principal Scientist II and $152,600/year to $283,400/year for Senior Principal Scientist; however, while salary ranges are effective from 1/1/25 through 12/31/25, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

#ModelingAndSimulation #PKSciences #TranslationalMedicineQuants

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers who are focused on building and advancing a culture of inclusion that values and celebrates individual differences, uniqueness, backgrounds and perspectives. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to fostering a diverse and inclusive workplace that reflects the world around us and connects us to the patients, customers and communities we serve.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [e-mail] or call [phone] and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

$119,700.00 - $222,300.00

Skills Desired

Algorithms, Data Engineering, Innovation, Mentorship, Modeling And Simulation, Simulation Software, Waterfall Model