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An established industry player is seeking a highly skilled Principal Scientist to join their innovative xRNA team in Cambridge, Massachusetts. This role focuses on the design and synthesis of therapeutic oligonucleotides, driving innovation in oligonucleotide chemistry, and collaborating with diverse teams to advance RNAi therapeutics. The successful candidate will possess a strong research background in oligonucleotide therapeutics and will be instrumental in optimizing designs for enhanced potency and safety. Join a community of passionate professionals dedicated to making breakthroughs that change patients' lives and contribute to a brighter future in biomedical research.
Job ID REQ-10048538
Apr 18, 2025
USA
Internal Title: Principal Scientist II
This position will be located at Cambridge, MA site and will not have the ability to be located remotely.
We are seeking highly skilled and motivated Principal Scientist to join our fast-paced xRNA team in Cambridge, Massachusetts. The xRNA team strives for excellence and drives a diverse portfolio of siRNA assets and platform innovation to attenuate gene expression via RNAi. Our xRNA team works collaboratively with diverse Therapeutics Area groups, the Global Discovery Chemistry and the Discovery Sciences to broaden the use of RNAi into extrahepatic tissues.
The successful candidate will have strong research track in discovery and optimization of oligonucleotide therapeutics and will provide key expertise in oligonucleotide synthesis, purification and platform innovation.
Key responsibilities
Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between: $114,100 and $211,900/year; however, while salary ranges are effective from 1/1/24 through 12/31/24, fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further, final pay determinations will depend on various factors, including, but not limited to geographical location, experience level, knowledge, skills, and abilities. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment.
Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together?
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The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Division Biomedical Research
Business Unit Pharma Research
Location USA
State Massachusetts
Site Cambridge (USA)
Company / Legal Entity U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.