Principal Scientist I, Energy Homeostasis

AbbVie Inc.; North Chicago (IL); On-site; USD 140,000 - 190,000; Full time

Benefits offered by this job

Paid time off

Medical/Dental/Vision insurance

401(k) plan

Long-term incentives

Job summary

AbbVie Inc. is seeking a Principal Scientist to advance the obesity pipeline by leading external innovation and diligence efforts.

The role focuses on identifying novel targets via literature reviews and coordinating cross-functional teams across neuroscience, immunology, and obesity disciplines. The candidate will analyze preclinical data, coordinate PoC studies with CROs and academic labs, and prepare detailed reports and presentations.

Qualifications

• PhD in neuroscience, biology or related field with post-doctoral training.
• 6+ years of independent research in academic or industry settings.
• Expertise in obesity-related CNS regulation and energy metabolism.
• Proven peer-reviewed publications.
• Proficient with AI tools and data analysis software.
• Capable of presenting at international conferences.
• Strong communication and organizational skills.
• Ability to manage time and work independently.
• Experience with cross-functional project work is a plus.

Responsibilities

• Support external collaborations and licensing to diversify AbbVie's obesity pipeline, leading Obesity Discovery in diligence teams.
• Conduct literature and intelligence reviews to identify approaches for obesity target discovery.
• Lead cross-functional teams to expand obesity targets into neurology and immunology.
• Coordinate in vitro/in vivo PoC studies with CROs and academic labs.
• Analyze preclinical data and ensure scientific integrity across the process.
• Prepare scientific reports and presentations on obesity assets.
• Design MoA experiments and review protocols for late-stage assets.
• Execute tasks with minimal supervision.

Skills

PhD in neuroscience/biology

Independent research

Publications

AI tools

Data analysis

Communication skills

Project management

Cross-functional collaboration

Time management

Attention to detail

Education

PhD in neuroscience/biology

Tools

AI tools

Graphing software

Data analysis tools

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Purpose

AbbVie is expanding its presence in Obesity Therapeutics and is seeking a Principal Scientist to participate in external innovation and diligence efforts to advance the early obesity pipeline. This individual will report to a scientific director of obesity and primarily focus on external innovation activities for obesity assets.

Responsibilities

• Support external collaborations and licensing opportunities to diversify the pipeline by serving as the Obesity Discovery lead in Search & Evaluation diligence teams. Use personal scientific expertise to advise on scientific merit and drive external innovation.
• Perform literature/intelligence searches to determine scientific and technical approaches for discovery of novel obesity targets emphasizing energy metabolism and energy expenditure leading to weight loss with potential utility in additional indications (neurological disorders, autoimmune disorders).
• Serve as the Obesity Discovery lead in cross functional teams to expand obesity targets into other key therapy areas at AbbVie including but not limited to neuroscience and immunology.
• Coordinate in vitro/in vivo PoC studies for preclinical assets, working with contract research organizations and academic labs to complete key preclinical experiments.
• Apply experience to analyze preclinical PK, in vitro, in vivo data sets for obesity related assets, and to ensure scientific integrity throughout the process.
• Prepare scientific reports and presentations related to pre-clinical obesity assets.
• Design MoA experiments, review protocols, and data sets for late-stage clinical assets.
• Responsible for completing these tasks with minimal supervision.

Qualifications

• Ph.D scientist with post-doctoral training in neuroscience, biology or related biological discipline
• 6+ years of independent research experience in industrial or academic setting
• Content expertise in obesity related scientific areas including CNS regulation of energy balance and peripheral energy metabolism, brain peripheral cross-talk and pharmacological manipulation of energy balance
• Proven record of scientific achievements as assessed by peer reviewed publications
• Proficient with AI tools, graphing and data analysis tools
• Capable of performing platform talks at international conferences
• Excellent organizational, oral and written communication skills
• Complex problem solving and excellent attention to detail
• Ability to manage time independently and effectively to achieve goals
• Experience in project management and cross functional/disciplines working is a plus

Key Stakeholders

Obesity Discovery Research Scientific Directors, Search & Evaluation Obesity Teams

Compensation and Benefits

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees. This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html