Principal Scientist I

AbbVie; Irvine (CA); On-site; USD 150,000 - 210,000; Full time

Benefits offered by this job

Comprehensive benefits package

Paid time off

Long-term incentive programs

Job summary

AbbVie is seeking a highly skilled scientist to direct an in vivo pharmacology team within Allergan Aesthetics Biological Research. The role focuses on designing and executing pharmacology studies to evaluate therapeutic proteins on muscle function, with leadership across matrixed teams and strong regulatory reporting.

A PhD in biology or related field plus 6+ years of experience is expected. The candidate will oversee assay development, data interpretation, and collaboration with neuroscience

Qualifications

• Extensive experience with pharmacological assays in vivo.
• Strong background in neuroscience and rodent anatomy/histology.
• Proven ability to lead matrixed project teams and mentor staff.
• Experience in data analysis and reporting for regulatory and publication purposes.
• Ability to communicate findings to cross-functional groups.

Responsibilities

• Lead a team of in vivo pharmacology scientists to design and perform pharmacology studies.
• Develop and implement novel assays and technologies to increase throughput and reproducibility.
• Mentor and develop team members; manage priorities and timelines.
• Collaborate with cross-functional teams to advance discovery programs into clinical studies.
• Present program updates to leadership and document findings in reports and regulatory filings.

Skills

In vivo pharmacology

Neuroscience

Data analysis

Team leadership

Regulatory understanding

Education

PhD in Biology or related field

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

Allergan Aesthetics Biological Research is seeking a highly motivated and innovative scientist to direct and contribute to multidisciplinary research in a highly collaborative environment. The successful candidate will lead a team of in vivo pharmacology scientists who design and perform pharmacology studies, using existing and novel assays to evaluate the effects of therapeutic proteins on muscle paralysis. The ideal candidate will be a recognized leader and technical expert in their field who will lead their team to execute effectively on critical research to address project and franchise needs.

The ideal candidate will have a strong, established background in pharmacology, with a specialization in In vivo pharmacology, and a proven track record of successfully leading diverse, matrixed project teams to advance novel therapeutics into development. The candidate will have experience in project conception, strategic planning, data analysis and interpretation of results; developing recommendations based on those results; and communicating findings at team meetings and in reports. The candidate will also have exceptional troubleshooting skills and a strong working knowledge of several research areas, including neuroscience, rodent anatomy, and histology. The candidate will be able to lead through influence and maintain a productive, collaborative, and inclusive laboratory environment in compliance with regulatory and company expectations.

Key responsibilities

• Demonstrate a high level of proficiency and expertise in his/her discipline.
• Drive functional excellence by leading team members in designing and performing in vivo assays, analyzing pharmacological results to answer scientific questions, and ensuring timely delivery of data and presentations.
• Set functional goals and experimental timelines and execute a strategy that aligns with the goals and key scientific objectives of the Biological Research department and the Neuroscience and Aesthetic Franchises.
• Manage team priorities and activities and develop the skills and careers of direct reports through effective mentoring, training, and supervision.
• Ensure the team understands the broad objectives of the projects they are supporting and their role in achieving them.
• Demonstrate creative ‘out of the box’ thinking to solve difficult problems, champion new technologies, and independently modify experimental plans when required to achieve project goals.
• Collaborate and develop strong working relationships with cross-functional team members to advance discovery programs into clinical studies, including potentially supporting later development goals.
• Make significant contributions to project teams through lab-based, or other work environment activities.
• Develop forward-looking strategies to identify and implement novel assays, measurements, and technologies that increase throughput, quality, and reproducibility of pharmacological results.
• Advance scientific expertise within the function and stay current on emerging literature and science, integrate new trends from internal and external sources into short-term functional objectives
• Provide expert advice and share knowledge with direct reports, peers, and senior management.
• Oversee data management and QC, author technical documents and publications, including protocols, study reports, relevant sections of regulatory filings, and other similar documents.
• Effectively organize and present program updates and research strategies to cross-functional partners and leaders across the discovery and development organizations.
• Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials, controlled drug, and animal welfare where applicable.

Qualifications

Job Qualifications (minimum requirements)

• Extensive experience with pharmacological assays, focusing on in vivo pharmacology in an industrial research environment, with at least 6+ years of experience managing teams and/or cross-functional projects.
• Direct experience with peripheral animal models and measurements is an advantage.
• Strong knowledge and experience in neuroscience, both central and peripheral, animal anatomy and histological assays and methods.
• Highly organized and self-directed, capable of leading multiple complex research programs in parallel.
• Detail-oriented, with a demonstrated commitment to accuracy and thoroughness in documenting experimental plans, timelines, study results, and technical reports.
• Demonstrated experience authoring and contributing to a variety of documentation and presentations, including technical reports and regulatory documents.
• Proven leadership and management abilities, including mentoring, guiding, supervising, and developing scientific personnel of varied backgrounds and training levels, while supporting multiple complex research programs in parallel
• Solid understanding of statistical analysis of scientific data using software tools (e.g., Prism, SigmaPlot, SPSS)
• Effective problem-solving skills, with the ability to lead teams to resolve issues and make sound strategic decisions
• Effective written and oral communication, and strong interpersonal skills for working with diverse internal groups and external partners
• Ability to create an inclusive environment where diverse ideas, viewpoints and backgrounds are valued; willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view.

Education & Experience

PhD in Biology, Pharmacology, Neuroscience, Biochemistry, or equivalent field with 6+ years of related work experience in biotech or pharma; Master’s Degree Science or PharmD with 12+ years of related work

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of thisposting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location,and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless anduntil paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html