Principal Scientist, Human Genetics

Boehringer Ingelheim; Ridgefield (CT); On-site; USD 140,000 - 222,000; Full time

Job summary

Boehringer Ingelheim is seeking a Principal Scientist to advance human genetics-driven drug discovery across diseases, including inflammatory, cardiorenal metabolic disorders and cancer immunology. You will lead analyses, interpret results and mentor teams in a global genetics program.

The role focuses on biobank-scale data, translational biomarker nomination and establishing proof of clinical concept, with significant project leadership responsibilities.

Qualifications

• PhD in Statistical Genetics, Genetic Epidemiology, Computational Biology, Statistics, Computer Science or related fields with genetics focus.

Responsibilities

• Partner with cross-functional teams to advance therapeutic strategies using human genetics.
• Contribute to analyses and build datasets with the global human genetics team.
• Lead strategic initiatives and share expertise across departments.
• Collaborate with external academic and industry partners.
• Contribute knowledge of biobank-scale clinicogenomic data and translational application.
• Plan and prioritize genetics analysis and communication for the project.

Skills

Genetics expertise

Programming experience

Collaboration

Project management

Education

PhD in Statistical Genetics or related field

Job description

Description

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

The focus of this role is to advance human genetics-driven drug discovery across multiple disease areas, including inflammatory and respiratory conditions, cardiorenal metabolic disorders, cancer immunology and others. In this role, the Principal Scientist brings deep hands‑on expertise in performing standard genetic analyses (eg., GWAS, meta-analysis, QTL evaluation), using biobank-scale datasets and interpretation of results to contribute to strategic objectives. These objectives include elucidation of disease biology, understanding mechanism of action for therapeutic candidates, safety assessment, translational biomarker nomination and establishing proof of clinical concept. Additional responsibilities include contributions to nominating first‑in‑class novel therapeutic concepts rooted in human genetics evidence. Direct participation in analysis, results interpretation and clear communication of results to an audience with diverse expertise is required. At this level, significant responsibilities in project leadership and team mentorship are expected.

@computationalinnovation

Duties & Responsibilities

• Partner with cross-functional teams to establish and advance therapeutic strategies, specifically contributing relevant evidence and innovative ideas from human genetics.

• Contribute to analyses, and to building datasets and analytic capabilities as needed in partnership with the global human genetics team to address research needs that can be addressed with genetics.

• Excel in strategic initiatives, offer insights and execute tasks at the level of a recognized subject matter expert.

• Effectively lead, collaborate, and communicate across internal departments and with external academic and industry partners

• Contributes knowledge and experience with biobank-scale clinicogenomic data sets and analytical methods, plus understanding of translational application

• Plans, structures and prioritizes genetics analysis, interpretation and communication activities appropriate for the research project strategy

Requirements

• PhD in Statistical Genetics, Genetic Epidemiology, or Computational Biology, Statistics, Computer Science or related fields with genetics focus

• 5 years of post-PhD industry experience in disease translation within a pharmaceutical or biotechnology environment

• In-depth biological and translational knowledge in one of the disease focus areas of Boehringer Ingelheim

• Strong genetics expertise demonstrated through successful disease translation applications and a proven track record of delivering value through human genomics

• Extensive computing and programming experience with demonstrated proficiency in relevant programming languages

• Strong collaborator and presenter with proven experience in driving impact within matrix environments

• Demonstrated project management expertise in leading cross-functional projects and teams

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction.

• Must be willing to take a drug test and post‑offer physical (if required)

• Must be 18 years of age or older

Compensation Data

This position offers a base salary typically between $140,000 and $222,000. The position may be eligible for a role specific variable or performance‑based bonus and or other compensation elements. For an overview of our benefits please click here. (https://www.boehringer-ingelheim.com/us/careers/benefits-rewards)

All qualified applicants will receive consideration for employment without regard to a person’s actual or perceived race, including natural hairstyles, hair texture and protective hairstyles; color; creed; religion; national origin; age; ancestry; citizenship status, marital status; gender, gender identity or expression; sexual orientation, mental, physical or intellectual disability, veteran status; pregnancy, childbirth or related medical condition; genetic information (including the refusal to submit to genetic testing) or any other class or characteristic protected by applicable law.