Principal Scientist, Genomic Technologies & Human Genetics

GlaxoSmithKline; Upper Providence (Delaware County); On-site; USD 121,000 - 202,000; Full time

Benefits offered by this job

Annual bonus

Health & retirement benefits

Paid holidays

Parental leave

Vacation

Job summary

GlaxoSmithKline is seeking a Principal Scientist in Genomic Technologies, Human Genetics and Genomics to drive causal gene-phenotype discoveries using large-scale genetic data. You will integrate computational and statistical methods to support drug discovery decisions.

The role involves collaboration across Translational Sciences, applying cutting-edge analytics and ensuring rigorous, reproducible research practices in a multi-site environment.

Qualifications

• PhD or equivalent in a relevant scientific discipline.
• Experience with large-scale biobank data (e.g., UK Biobank, All of Us).
• Strong programming skills in R and Python with reproducible research practices.

Responsibilities

• Evaluate and develop production implementations of genomic data analysis methods.
• Generate large-scale analysis outputs and visualizations of genetic data.
• Collaborate with discovery and translational teams to influence portfolio decisions.
• Stay informed about recent research and potential applications within GSK.
• Foster a culture of innovation, quality and continuous improvement.

Skills

R programming

Python programming

Communication

Teamwork

Cloud computing

Education

PhD or equivalent

Tools

SQL

PySpark

BigQuery

Docker

Nextflow

Job description

GlaxoSmithKline is seeking a Principal Scientist in Genomic Technologies, Human Genetics and Genomics to drive causal gene-phenotype discoveries using large-scale genetic data. You will integrate computational and statistical methods to support drug discovery decisions.

The role involves collaboration across Translational Sciences, applying cutting-edge analytics and ensuring rigorous, reproducible research practices in a multi-site environment.