Principal Scientist, Early Cancer Detection

InVitro Cell Research, LLC; Englewood (NJ); On-site; USD 165,000 - 205,000; Full time

Job summary

A leading biomedical company in Englewood, NJ, is seeking a Principal Scientist to lead the Cancer Early Detection Team. This role focuses on building systems to predict cancer signatures using blood and urine biomarkers, requiring a PhD and extensive cancer research experience. The position offers a competitive salary range of $165,000 to $205,000 per year, along with an annual bonus structure. Candidates must have programming experience in R and Python, alongside in-depth knowledge of cancer diagnostics and prevention.

Qualifications

• At least 10 years of cancer research experience, preferably in early detection and biomarkers.
• Current knowledge of cancer screening and diagnostics.
• Experience with prediction modeling and machine learning.

Responsibilities

• Lead a cancer biomarkers group for early stage detection.
• Collaborate on molecular and cancer prevention screening assays.

Skills

Cancer research

Machine learning

Biostatistics

Programming in R

Programming in Python

Education

PhD or MD

Tools

R

Python

Job description

Overview

Principal Scientist, Early Cancer Detection at InVitro Cell Research, LLC. The program focuses on building early warning systems from blood- and urine-based biomarkers using machine learning to predict cancer signatures for early intervention. We are hiring a Principal Scientist to lead the Cancer Early Detection Team.

Compensation

Base pay range: $165,000.00/yr - $205,000.00/yr

Additional compensation types: Annual Bonus

Starting base pay range: $165,000/yr - $205,000/yr

Position title and compensation are commensurate with experience.

Responsibilities

• Lead a cutting-edge cancer biomarkers group to detect cancer at its earliest stages
• Contribute practical and translatable pan-cancer screening/early detection, diagnostic, prevention and therapeutic ideas
• Quantify and track cancer biomarkers, including CTCs, cfDNA, serum, plasma, and urine proteins, RNA, metabolites, driver-gene mutations, epigenetic modifications, etc.
• Collaborate with ICR's Biomarkers Team to perform molecular and cellular cancer prevention screening assays under a personalized medicine paradigm

Qualifications

• A PhD, MD or both
• At least 10 years of cancer research experience, preferably in early detection and biomarkers
• Current and in-depth knowledge of pan-cancer: screening, early detection, biomarkers, diagnostic prediction, genetics, prevention, and chemical- and vaccine-therapeutics (practical and experimental)
• Programming experience in R and Python
• Solid grasp of biostatistics, especially probability theory
• Experience with prediction modeling and machine learning, including proper scoring rules

Preferred qualifications

• Expert knowledge of worldwide cancer biomarker and detection assay development pipelines
• Experience with cell-based assays, immunofluorescent microscopy, qPCR, flow cytometry, single-cell genomics, RNAseq, cell culture, organoid culture, Illumina NextSeq 550, DNA methylation sequencing, ddPCR, Luminex, clinical chemistry instrumentation, Kryptor, Access 2, robotic liquid handling (e.g. Tecan), Vortex, and DepArray
• Experience with protein, RNA, and small metabolite cancer biomarker analysis

Other requirements

• An easygoing, friendly personality
• The ability to work in the United States without sponsorship

Other job details

Seniority level: Mid-Senior level

Employment type: Full-time

Job function: Research and Science

Location: Englewood, NJ (site details not included here)