Principal Research Scientist II, Analytical R&D

AbbVie Inc; North Chicago (IL); On-site; USD 100,000 - 140,000; Full time

Job summary

A leading pharmaceutical company is seeking a Principal Research Scientist II for its Analytical R&D team. In this role, you will lead a team of scientists to develop analytical strategies for new chemical entities and contribute to drug development from preclinical to clinical phases. The ideal candidate will have significant experience in analytical chemistry, leadership capabilities, and a proven track record of innovation in a fast-paced environment.

Benefits

Comprehensive benefits package including medical/dental/vision insurance

401(k) to eligible employees

Paid time off including vacation and sick days

Participation in short-term incentive programs

Qualifications

• Minimum of 14 (BS), 12 (MS), or 6 (Ph.D.) years related industry experience.
• Strong background in analytical techniques and troubleshooting methods.
• High-quality communication skills and ability to work in teams.

Responsibilities

• Lead a team to support development of NCE candidates from preclinical to Phase II.
• Responsible for method development and testing procedures.
• Generate scientific proposals and lead them.

Skills

Analytical Problem-Solving

Method Development

Team Leadership

Innovation

HPLC Analysis

Education

Bachelors, Masters, or Ph.D. in Analytical Chemistry

Tools

HPLC

Dissolution

GC

NMR

MS

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative small molecule medicines and spans from the selection of Discovery candidate molecules through Early-Stage Clinical Development. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVie's pipeline of innovative medicines. Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Position Description:

For thePrincipal Research Scientist II position, we are seeking a highly motivated, experienced analytical scientist to lead a small team of analytical scientists supporting early phase development of New Chemical Entities (NCEs) drug substance and drug product in both preclinical and clinical programs. The candidate should have extensive expertise in applying regulatory guidelines within an R&D environment with a fit for purpose mind set. The candidate will need experience in analytical control strategies, analytical method development, characterization, validation, release, and stability testing.

He/she should be able to perform research along with directing research and/or project activities by effectively mentoring, guiding and/or supervising scientific personnel. Should conceive, execute and communicate novel multi-disciplinary research or development strategies that achieve project and strategic goals. Serve as an analytical project lead scientist on projects and contribute scientific insights into multiple other projects and initiatives.

He/she must foster productive collaborations within the global Analytical R&D organization and with R&D cross-functional partners such as Pre-Clinical Safety, Process Chemistry, Process Engineering, Drug Product Development, Molecular Profiling and Drug Delivery, Quality Assurance and CMC-Regulatory.

Responsibilities:

• Mentor/supervise a team to support the development of NCE candidates (RSM to API to DP) from pre-clinical through Phase II clinical trials and accountable for the effective performance of the team/individuals.
• Responsible for method development, testing procedures, and implementation of analytical control strategies to help the advancement of drug discovery candidates.
• Apply analytical separation and detection modes for complex impurity profiling of pharmaceutical products.
• Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
• Utilize understanding of a range of analytical techniques to conduct research and development studies related to small-molecule drug products, active pharmaceutical ingredients, intermediates, starting materials, impurities and impurity profiling.
• Routinely demonstrate scientific initiative and creativity in research or development activities and maintain a high level of productivity in the lab.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
• Encourage ideas and drive for continuous improvement and champion initiatives within Analytical R&D and across R&D partner functions.
• Raises the bar and is never satisfied with the status quo.
• Understand and comply with AbbVie safety, quality and regulatory policies and government regulations.

Qualifications

Qualifications

• Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 14 (BS), 12 (MS), or 6 (Ph.D.) years related industry experience.
• Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshoot analytical methods.
• Demonstrate creative 'out of the box' thinking to solve difficult problems and
• Champion new technologies to achieve project goals.
• Hands on experience with HPLC analysis and method development along with fundamental understanding and working knowledge of various analytical techniques including Dissolution, MS, GC, and NMR.
• Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
• Experience in the use of computerized data handling systems.
• High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.
• Learns fast, grasps the "essence" and can change course quickly where indicated.
• High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

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