Principal Research Scientist II, Analytical Development ( On-site, Waltham MA)

AbbVie Inc; Waltham (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

AbbVie Inc is seeking an analytical lead for their Analytical Development – Waltham team. The role involves leading a highly skilled team to develop methods for antibody drug conjugates (ADCs), requiring a strategic thinker with a strong technical background in analytical chemistry. Successful candidates will have a PhD or Master's degree, along with extensive experience in CMC analytical development and solid leadership capabilities.

Benefits

Comprehensive medical/dental/vision insurance

401(k) plan

Paid time off

Short-term incentive programs

Long-term incentive programs

Qualifications

• 8+ years of experience with a PhD or 14+ years with a Master’s.
• Proven track record as a principal investigator.
• Strong interpersonal skills with collaborative groups.

Responsibilities

• Lead the analytical team, managing complex projects.
• Optimize methods and implement automation technologies.
• Communicate project strategies and manage stakeholder expectations.

Skills

Technical expertise in CMC analytical chemistry

Ability to lead an analytical team

Project management

Education

PhD in analytical chemistry or related field

Master’s Degree in relevant discipline

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

Purpose:

Abbvie Product Development Science and Technology (PDS&T) Analytical Development – Waltham is responsible for CMC analytical development activities for antibody drug conjugates (ADCs). We are building a team of highly skilled scientists and technical leaders in ADC development to drive the advancement of targeted cancer therapies to improve patient’s lives. The Analytical Development- Waltham team is responsible for late-phase to commercial method development, optimization, validation, advanced characterization, process development support, regulatory authoring, and control strategy for ADCs. The team works cross-functionally with process development, regulatory, and quality within the Abbvie network and with contract manufacturing organization and contract laboratories. The Analytical Development – Waltham team is searching for an analytical lead responsible for optimizing and delivering robust methods, reliable results to support process development, designing and implementing automation technologies for mAbs and ADCs. This role requires a strategic thinker with a strong technical analytical background and the ability to lead an analytical team, manage complex projects, and effectively communicate cross-functionally.

Responsibilities:

• • Lead analytical team, translating development objectives into actionable analytical activities.
  • Provide technical expertise to analysts in physiochemical analytical methods such as SEC, CE-SDS and iCIEF.
  • Establish collaborations across the organization to support method optimizations and transfers to PDST analytical teams.
  • Design and implement robust automation technologies to provide efficient data collection and analysis.
  • Manage and prioritize analysis to support multiple ADC programs.
  • Interpret and identify data trends in key analytical release and stability assays.
  • Act as the principal contact for all stakeholders and balance conflicting expectations between PDS&T and Analytical areas.
  • Communicate project strategy, key issues, and risks to relevant teams and escalate risks and facilitate resolution within/across functional areas.

Qualifications

• • PhD in analytical chemistry or related field with 8 years of related experience; Master’s Degree with 14 years of related experience
  • Technical expertise in CMC analytical chemistry
  • Demonstrated ability to function as a principle investigator, generating original technical ideas and research or development strategies
  • Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

• This job is eligible to participate in our short-term incentiveprograms.

• This job is eligible to participate in our long-term incentiveprograms

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html