Principal Research Scientist I, Biologics Analytical Research & Development

ZipRecruiter; North Chicago (IL); On-site; USD 90,000 - 150,000; Full time

Job summary

An innovative biopharmaceutical company is seeking a skilled scientist to lead the development of advanced analytical techniques for biologics. This role involves working with global teams to drive product development strategies and enhance analytical capabilities. The ideal candidate will leverage their expertise in mass spectrometry and protein characterization to contribute to the company's pipeline of therapeutic biologics. Join a collaborative environment where your scientific insights will help shape the future of medicine and improve patient outcomes. If you are passionate about advancing healthcare through innovative solutions, this opportunity is for you.

Benefits

Paid Time Off

Health Insurance

401(k)

Incentive Programs

Qualifications

• 6+ years of experience in analytical development for biologics.
• Deep knowledge of protein characterization and biophysical techniques.

Responsibilities

• Lead development of LC-MS methods for biologic programs.
• Participate in cross-functional teams to guide analytical strategy.

Skills

Analytical Chemistry

Biochemistry

Mass Spectrometry

Protein Characterization

HPLC Techniques

Interpersonal Skills

Education

PhD in Analytical Chemistry or related field

Tools

LC-MS

HPLC

Job description

Job Description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn, and TikTok.

Job Description

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader to develop and market advanced therapies that address some of the world's most complex and serious diseases.

AbbVie Biologics Analytical Research & Development (Biologics Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of discovery candidate molecules through the transition of analytical methods and testing to support product launch. We are building a world-class team of scientists and leaders to advance industry-leading analytical capabilities and contribute meaningfully to AbbVie's pipeline of medicines. Careers in AbbVie Biologics Analytical R&D offer opportunities to work with global and cross-functional teams to drive science and product development strategies.

The biologics characterization group develops advanced analytical techniques for in-depth characterization of therapeutic proteins and biologic molecules using mass spectrometry and other techniques. We seek diverse candidates with strong scientific and leadership experience to join our team. The ideal candidate will have CMC expertise in analytical development for biologics, assisting with method development and execution to support CMC, and participating in phase-appropriate characterization at all development stages.

Key Responsibilities

1. Lead development and implementation of LC-MS based extended characterization methods for complex biologic programs at various phases, including experience with ADCs.
2. Participate in cross-functional teams to guide analytical strategy and support process and formulation scientists, sharing expertise and fostering collaboration.
3. Advance scientific expertise, mentor colleagues, and contribute to overcoming scientific and business challenges.
4. Ensure quality and effectiveness of project results through sound design, risk assessments, and fallback strategies.
5. Identify and integrate emerging scientific trends in molecular characterization of biotherapeutics.
6. Apply innovative approaches and create new methods or strategies for biologic analysis.
7. Contribute significantly to project teams, working across disciplines to meet milestones.
8. Generate and lead scientific proposals, responding to advances and threats with new strategies.

Qualifications

• PhD with 6+ years’ experience in Analytical Chemistry, Biochemistry, or Biology, with laboratory experience.
• Deep knowledge of protein characterization by mass spectrometry and biophysical techniques.
• Practical experience with protein HPLC (SEC, IEX, HIC), electrophoresis, and separation techniques.
• Understanding of protein chemistry, biologics drug development, and formulations; experience with ADCs is a plus.
• Proven innovative ability and history of product release improvements.
• Strong interpersonal skills for collaboration with internal and external partners.

Additional Information

This position is on-site at AbbVie's campus in North Illinois. The salary range is indicative; actual pay depends on various factors. Benefits include paid time off, insurance, 401(k), and participation in incentive programs. Compensation details are at the company's discretion and subject to change.

AbbVie is an equal opportunity employer committed to integrity, innovation, and community service. We welcome applicants seeking accommodations and encourage diverse candidates to apply.