Principal Research Associate - Gene Delivery & Expression

Vertex Pharmaceuticals Inc (US)

United States

On-site

USD 88,000 - 132,000

Full time

14 days+

A complete application in a minute

Tailored resume and cover letter, ready to send.

Get past ATS filters

Benefits offered by this job

Annual bonus

Annual equity awards

Paid time off

Educational assistance programs

Student loan repayment

Commuting subsidy

401(k)

Job summary

Vertex Pharmaceuticals Inc is seeking a Principal Research Associate to advance non-viral gene therapy candidates. The role emphasizes designing and executing molecular and cellular assays to support Duchenne Muscular Dystrophy programs and to generate high-quality data for discovery-stage decisions.

This on-site role requires deep hands-on expertise in molecular cloning, qPCR/RT-qPCR, and protein-based assays, with collaboration across cross-functional teams and external partners.

Qualifications

Master’s Degree (or equivalent) and 8+ years of relevant employment experience.
Bachelor’s Degree (or equivalent) and 10+ years of relevant employment experience.
Significant hands-on laboratory experience in molecular cloning, molecular biology assays, cell biology assays, and protein-based assays.

Responsibilities

Build gene expression constructs using advanced molecular biology tools.

Skills

Molecular biology

Cell biology

Gene-expression analysis

Protein-based assays

qPCR

RT-qPCR

NGS library construction

ELISA / MSD

Western blot

Data communication

Education

Master’s Degree in biological sciences

Bachelor’s Degree in biological sciences

Tools

Benchling

qPCR instrumentation

Western blot equipment

Job description

This on-site role requires deep hands-on expertise in molecular cloning, qPCR/RT-qPCR, and protein-based assays, with collaboration across cross-functional teams and external partners.

Get your free, confidential resume review.

or drag and drop your file here.