Principal Project Manager - Project Delivery

US74 Lonza Manufacturing LLC; Vacaville (CA); On-site; USD 160,000 - 266,000; Full time

Benefits offered by this job

Performance-related bonus

Medical, dental and vision insurance

401(k) matching plan

Life insurance

Short-term disability insurance

Long-term disability insurance

Employee assistance programs

Paid Time Off

Job summary

Lonza Group Ltd. in Vacaville, CA, seeks a Principal Project Manager to lead end-to-end capital and expense projects at the site.

The role emphasizes strict budget control, cGMP compliance, and collaboration with Global Engineering and site functions to safely deliver manufacturing upgrades and new construction. Lead cross-functional teams through design, commissioning and closeout, while aligning expectations with senior leadership and procurement to optimize contracts and resources.

Qualifications

• Bachelor’s Degree in Chemical or Mechanical Engineering.
• Proven expertise in end-to-end project execution, spanning scope definition, engineering design, procurement, construction, commissioning, start-up, and closeout.
• Strong executive accountability for strict budget management, accelerated delivery schedules, and enterprise milestone targets.
• Executive-level oversight of complex, highly regulated operational environments, ensuring absolute compliance with local, federal, and EHS standards.
• Exceptional ability to align expectations, communicate risks, and drive strategic alignment with senior leadership, legal, procurement, and client teams.
• Advanced expertise in orchestrating internal resources and partnering with procurement to negotiate high-value contractor and supplier agreements.
• Champion of continuous improvement, evolving site-wide project procedures, governance frameworks, and automation infrastructure.

Responsibilities

• Lead end-to-end delivery of complex cGMP facility modifications, tech transfers, and capital projects from design through commissioning and closeout.
• Own project performance by strictly managing budgets and meeting milestone schedules for manufacturing upgrades and new construction.
• Ensure all engineering, construction, and operational activities strictly adhere to federal, state, local, and EHS regulatory requirements.
• Communicate project objectives, risks, and milestone status with senior management, client teams, procurement, legal, and F&E leadership.
• Partner with procurement to develop, negotiate, and manage external contracts and internal resources to optimize project delivery.
• Proactively identify project risks, resolve cross-functional conflicts, and align stakeholder expectations to ensure successful outcomes.
• Continuously refine project management procedures and ensure full compliance with internal project governance standards.

Skills

End-to-end project execution

Budget management

Regulatory compliance

Executive alignment

Procurement negotiation

Continuous improvement

Education

Bachelor’s Degree in Chemical or Mechanical Engineering

Job description

Location: Vacaville, California. This is a fully site-based role. Working together in person supports close, real-time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards. The Principal Project Manager (PM) is responsible for managing capital and expense (non-capital) projects at the Vacaville site. This position ensures safe delivery, compliance with all applicable requirements, including cGMP quality, risk, schedule and budget. The PM shall work closely with Global Engineering, and colleagues in Vacaville Facilities and Engineering (F&E), Manufacturing, Manufacturing Science and Technology (MSAT), Safety Health Environment (SHE) and Quality Departments.

What you will get

The full-time base annual salary for this position is expected to range between $159,750 to $266,250.

• Performance-related bonus
• Medical, dental and vision insurance
• 401(k) matching plan
• Life insurance, as well as short-term and long-term disability insurance
• Employee assistance programs
• Paid Time Off

What you will do

• Lead end-to-end delivery of complex cGMP facility modifications, tech transfers, and capital projects from design through commissioning and closeout.
• Own project performance by strictly managing budgets and meeting milestone schedules for manufacturing upgrades and new construction.
• Ensure all engineering, construction, and operational activities strictly adhere to federal, state, local, and EHS regulatory requirements.
• Communicate project objectives, risks, and milestone status with senior management, client teams, procurement, legal, and F&E leadership.
• Partner with procurement to develop, negotiate, and manage external contracts and internal resources to optimize project delivery.
• Proactively identify project risks, resolve cross-functional conflicts, and align stakeholder expectations to ensure successful outcomes.
• Continuously refine project management procedures and ensure full compliance with internal project governance standards.

What we look for

• Bachelor’s Degree in Chemical or Mechanical Engineering.
• Proven expertise in end-to-end project execution, spanning scope definition, engineering design, procurement, construction, commissioning, start-up, and closeout.
• Strong executive accountability for strict budget management, accelerated delivery schedules, and enterprise milestone targets.
• Executive-level oversight of complex, highly regulated operational environments, ensuring absolute compliance with local, federal, and EHS standards.
• Exceptional ability to align expectations, communicate risks, and drive strategic alignment with senior leadership, legal, procurement, and client teams.
• Advanced expertise in orchestrating internal resources and partnering with procurement to negotiate high-value contractor and supplier agreements.
• Champion of continuous improvement, evolving site-wide project procedures, governance frameworks, and automation infrastructure.

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of. Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law.

Ready to shape the future of life sciences? Every day, our teams across the world work together to turn scientific breakthroughs into life-changing medicines that reach up to 100 million patients a year. Lonza is a place where people can make a unique impact, grow their careers and belong.

You will feel at home at Lonza if you:

• Take ownership, step forward, and enjoy meaningful responsibility
• Love solving problems and thrive in a complex, fast-moving environment
• Are curious, always looking to learn and improve
• Work collaboratively, contributing to something bigger than yourself
• Are motivated to make a difference through work that impacts customers and their patients

Why Lonza:

• We are a place of unique opportunity, where your ideas, expertise and ambition can make a real difference.
• Here, you will have the freedom to grow, the support to succeed and the chance to contribute to work that matters.
• We are the makers of the medicines of tomorrow.
• Join us.
• Be you.