Principal Investigator, MD — Patient-Centered Trials Leader

Civia Health, LLC.; Independence (MO); On-site; USD 150,000 - 230,000; Full time

Benefits offered by this job

Competitive compensation

Medical, dental, and vision insurance

Generous PTO and paid holidays

Flexible scheduling options

Professional development support

Mission-driven team values

Job summary

Civia Health, LLC. is seeking an experienced Principal Investigator to oversee Phase 2–4 clinical trials. You will ensure scientific integrity, patient safety, and regulatory compliance while guiding a collaborative, mission-driven team.

Ideal candidates will hold an MD or DO with an active license and have 3+ years of PI experience, plus strong knowledge of GCP and FDA regulations. The role includes potential travel for audits and site visits, with a focus on patient-centered care and ethical

Qualifications

• MD or DO with active, unrestricted license.
• 3+ years as Principal Investigator in clinical research (Phase 2–4 preferred).
• Board certification in internal medicine, endocrinology, or related field preferred.
• Strong knowledge of GCP, FDA regulations, and clinical operations.
• Excellent leadership, communication, and problem-solving skills.
• Passion for innovation, ethics, and patient-centered care.

Responsibilities

• Serve as the physician of record and lead clinical oversight for assigned trials.
• Review and approve study protocols, informed consent documents, and source documentation.
• Conduct physical exams, medical reviews, and oversee safety assessments for participants.
• Ensure compliance with all ICH-GCP, FDA, and IRB regulations.
• Provide guidance and mentorship to the clinical research team.
• Engage with sponsors, monitors, and regulatory bodies as needed.
• Occasional travel may be required for audits, site visits, or team meetings.

Skills

GCP knowledge

Leadership

Communication

Problem solving

Patient-centered care

Education

MD/DO

Board certification in internal medicine or endocrinology

Job description

Civia Health, LLC. is seeking an experienced Principal Investigator to oversee Phase 2–4 clinical trials. You will ensure scientific integrity, patient safety, and regulatory compliance while guiding a collaborative, mission-driven team.

Ideal candidates will hold an MD or DO with an active license and have 3+ years of PI experience, plus strong knowledge of GCP and FDA regulations. The role includes potential travel for audits and site visits, with a focus on patient-centered care and ethical