Principal Investigator/Bioanalytical Lead Scientist I- (LC-MS)

BIO Labcorp Bioanalytical Services LLC; Madison (WI); On-site; USD 80,000 - 95,000; Full time

Benefits offered by this job

Medical, Dental, Vision, Life

401(k)

PTO / Flexible Time Off

Job summary

Labcorp in Madison, WI seeks a Principal Investigator / Bioanalytical Lead Scientist I – LCMS to lead scientific work supporting external methods and projects within GLP/GCP-regulated studies. You will ensure regulatory compliance, develop analysis protocols, and review data for validation and timely data delivery.

The role requires strong leadership, excellent communication, and experience with LC-MS, GLP, and bioanalytical method development/validation.

Qualifications

• Bachelor’s degree in Chemistry or Biology with 3–4+ years’ experience supporting lead scientific projects.
• 2+ years’ GLP experience required.
• 2+ years’ Liquid Chromatography–Mass Spectrometry experience required.

Responsibilities

• Leads and directs scientific work to support external methods and projects.
• Serves as a SD, RS, CS, LS, or PI for GLP- and GCP-regulated studies as applicable.
• Ensures client programs meet regulatory requirements and milestones in the drug development pathway.
• Develops and reviews protocols and sample analysis plans.
• Reviews data with the Method Development Team to ensure methods are ready for validation.

Skills

GLP

LC-MS

Bioanalytical MDD/Validation

Education

Bachelors in Chemistry or Biology

Masters degree preferred

Tools

Watson

Nautilus

Analyst software

Job description

Labcorp is a global leader in laboratory services, providing the insights and answers that help healthcare providers, patients, researchers, pharmaceutical companies and health systems make confident decisions and improve outcomes. Through our unparalleled science, data, technology and laboratory network, we advance diagnostics, accelerate innovation and help address some of the world’s most important health challenges. As we shape the future of healthcare, we are leveraging advanced technologies, intelligent digital solutions and data-driven innovation across our operations to enhance how work gets done and deliver greater value to customers and patients. With our global scale and deep expertise, you’ll have the opportunity to do meaningful work, grow your career and make a real impact on people’s health around the world. Together, we’re improving health and improving lives.

Principal Investigator / Bioanalytical Lead Scientist I – LCMS

Labcorp is seeking Principal Investigator / Bioanalytical Lead Scientist to join our team in Madison, WI Team. Work Schedule: Monday – Friday, Day Shift

Job Responsibilities:

• Leads and directs scientific work to support external methods and projects.
• Serves as an SD, RS, CS, LS, or PI for non-regulated, GLP-regulated, and GCP-regulated studies as applicable.
• Ensure client programs meet Labcorp, client, and regulatory requirements in order to meet defined milestones along the drug development pathway.
• Develops and reviews protocols and sample analysis plans.
• Reviews data with the Method Development Team to ensure methods are ready for validation.
• Approves validation methods and reviews sample analysis methods.
• Independently reviews and approves raw data.
• Ensuring that any circumstances that may affect the quality and integrity of the study are identified and documented as they occur and appropriate corrective action is taken.
• Effectively evaluates data and tables to ensure regulatory guidelines and expectations are met.
• Reviews and approves reports for scientific accuracy and completeness.
• Ensures on-time delivery of high-quality data and reports.
• Provides technical support as needed.
• Leads efforts to troubleshoot and solve assay problems.
• Recognizes the functions of different teams within Labcorp and seeks guidance when appropriate.
• Manages scientific investigations.
• Approves QA project specific inspections.
• Approves data archival.
• Evaluates new proposals for technical feasibility.
• Supports scientific papers or posters which are published or presented at scientific meetings.
• Serves as the scientific point of contact for the client.
• Effectively work with the client to determine project requirements.
• Leads preinitiation meetings when needed.
• Gives scientific directives to the study team.
• Identifies scientific issues or scope changes within the study.
• Communicates and monitors scientific expectations with scientific staff and clients.
• Proactively identify ways to increase client satisfaction.
• Participates in client visits as a scientific lead.
• Responds to unscheduled deadlines, client needs, and crises without neglecting other responsibilities.
• Assist clients with experimental design outside the scope of SOPs.
• Develops and delivers compelling messages that connect with the audience.
• Promotes quality within the study team.
• Provides a technical resource for less experienced team members.
• Actively promotes collaboration across groups.
• Communicates successes and provides positive recognition to team members.
• Promotes a positive impression of Labcorp internally and within the industry.
• Provides technical and scientific guidance to clients and other departments.
• Leads new employee training and develops training materials and schedules.
• Identifies process improvement opportunities, participates in execution of initiatives.
• Advocates Labcorp ethics, vision, and values; fosters a high-performance culture.
• Participates in projects and tasks in addition to leading scientist responsibilities.
• Regularly provides support to other lead scientists or project managers.
• Mentors other employees.
• Able to plan, prioritize, and manage workload for large and complex projects.
• Demonstrated ability to manage high volume study work for key clients.
• Takes accountability and demonstrates responsibility regarding scientific study conduct.
• Good knowledge of client requirements.
• Manages time effectively.
• Performs other related duties as assigned.

Minimum Qualifications:

• Bachelor’s degree (Chemistry, Biology) 3-4 years or more experience supporting lead scientific projects that support external methods and projects
• 2 years or more Good Laboratory Practice (GLP), and Liquid Chromatography Mass Spectrometry experience required
• 2 years or more Bioanalytical Method Development and Validation required

Preferred Qualifications:

• Masters (MS) degree in science (Chemistry, Biology etc.) or related field preferred 1 year or more experience
• Watson, Nautilus, and Analyst software 1 year or more experience
• Root Cause Analysis 2 years or more experience working with regulatory agency guidelines and SOP's

Additional Job Standards:

• Excellent communication and interpersonal skills
• Proven ability to prioritize and manage time
• Excellent attention to detail
• Able to utilize word processing, databases, spreadsheet, and specialized software

Benefits:

• Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical, Dental, Vision, Life, STD/LTD, 401(k), Paid Time Off (PTO) or Flexible Time Off (FTO), Tuition Reimbursement and Employee Stock Purchase Plan.
• Employees regularly scheduled to work less than 20 hours, Casual, Intern, and Temporary employees are only eligible to participate in the 401(k) Plan.
• For more detailed information, pleaseclick here.

Application Window: 10/16/26 thru 10/31/2026

Pay Range: $80k – $95k annually All job offers will be based on a candidate’s skills and prior relevant experience, applicable degrees/certifications, as well as internal equity and market data.

Labcorp is proud to be an Equal Opportunity Employer: Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. Additionally, all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.

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We believe in the power of science to change lives. Labcorp is a leading global life sciences company that provides vital information to help doctors, hospitals, pharmaceutical companies, researchers, and patients make clear and confident decisions. Through our unparalleled diagnostics and drug development capabilities, we provide insights and accelerate innovations to improve health and improve lives. Here, you can join our nearly 70,000 employees, serving clients in more than 100 countries, as we work together to transform approaches to patient care.