Principal Feasibility Analyst

ICON; Center Square (PA); Remote; USD 120,000 - 180,000; Full time

Benefits offered by this job

Annual leave entitlements

Health insurance

Retirement planning

Global Employee Assistance Program

Job summary

ICON Strategic Solutions is seeking a Feasibility Manager to lead feasibility strategy across sponsor-dedicated programs. Reporting to Feasibility leadership, you will guide enrollment forecasting, site assessments, and data-driven decision making to accelerate clinical studies in rare diseases.

In a global, cross-functional, fast-paced environment, you will mentor junior team members, present insights to senior leadership, and partner with study teams to optimize trial delivery while

Qualifications

• Bachelor’s degree in a scientific or allied health field, with 7+ years in clinical research or feasibility.
• 5+ years hands-on operational feasibility experience.
• Experience leading feasibility strategy for complex studies or programs.
• Strong data synthesis and enrollment forecasting abilities.

Responsibilities

• Lead feasibility strategy and execution at the study level, supporting trial optimization and delivery of key milestones, while aligning with program-level standards.
• May serve as feasibility lead for a disease area or program, owning end-to-end feasibility across studies within that program.
• Synthesize and analyze feasibility, operational, and enrollment data from multiple sources to develop insights and recommendations.
• Translate findings into data-driven enrollment assumptions, risk assessments, and strategic recommendations.

Skills

Feasibility leadership

Enrollment forecasting

Data analysis

Excel proficiency

Cross-functional collaboration

Education

Bachelor’s degree in a scientific or allied health field

Tools

Forecasting tools

Job description

Feasibility Manager

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.

As the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

Reporting to the Director or Associate Director of Feasibility, the Principal Feasibility Analyst plays a critical role within the Patient and Site Engagement (PSE) Feasibility team, providing feasibility leadership across a range of rare disease programs to support the acceleration of clinical studies. Working closely with study teams and in alignment with Feasibility Leadership, this role leads feasibility strategy and execution for assigned studies, delivering high quality operational and site feasibility analyses that inform study planning and enrollment strategy.

For select assignments, this role may take on program‑level feasibility leadership for a disease area while remaining embedded at the study level, with scope and accountability defined in partnership with Feasibility leadership.

Key Responsibilities

• Lead feasibility strategy and execution at the study level, supporting trial optimization and delivery of key milestones, while ensuring alignment with broader program objectives and feasibility standards set at the program level.
• May serve as feasibility lead for an assigned disease area or program, assuming end‑to‑end feasibility ownership across studies within that program while continuing to lead feasibility execution at the study level, under the strategic oversight of a Director or Associate Director.
• Synthesize and analyze feasibility, operational, and enrollment data from multiple internal and external sources to develop a comprehensive understanding of therapeutic areas, standard of care, disease progression, patient and site profiles, and the competitive landscape.
• Evaluate the clinical trial landscape and apply advanced data mining and analytical approaches, including complex enrollment modeling and forecasting, to translate findings into data driven enrollment assumptions, risk assessments, and strategic recommendations at the study level.
• Operate effectively in a fast paced, dynamic study environment, demonstrating the ability to rapidly assess changing study inputs, reprioritize work, and adjust feasibility approaches to meet tight timelines and evolving study needs.
• Apply strong time management and prioritization skills to balance multiple studies and last minute requests, while maintaining analytical rigor and clear communication with stakeholders.
• Serve as a key feasibility partner with cross functional study teams, clearly communicating feasibility insights, assumptions, risks, and recommendations to support study planning, site selection, and enrollment strategy decisions.
• Lead and deliver data driven presentations with cross functional teams and in governance forums, clearly articulating feasibility insights, risks, and recommendations, including presenting analyses and responding to questions in meetings with senior leadership, as appropriate.
• Mentor and provide guidance to junior feasibility team members, supporting development of analytical skills, feasibility best practices, and consistency in deliverables at the study level.
• Apply strong operational judgment and clinical trial expertise to proactively identify challenges, anticipate risks, and drive solutions that support high quality feasibility execution across assigned studies.
• Contribute to the continuous improvement of feasibility processes, tools, and best practices, sharing insights and lessons learned from experience at the study level to inform broader team and program approaches.

Your Profile

• Bachelor’s degree in a scientific or allied health field (or equivalent industry experience), with 7+ years of progressive experience in clinical research, feasibility, clinical operations, or study startup within a sponsor or CRO environment, including a minimum of 5 years of hands‑on operational feasibility experience supporting complex studies or programs.
• Demonstrated experience leading feasibility strategy for complex studies or programs, with a proven track record of influencing decisions at the program or portfolio level related to site selection, enrollment strategy, and study acceleration.
• Experience working across multiple therapeutic areas or late phase programs, with increasing strategic accountability.
• Demonstrated ability to analyze, synthesize, and interpret complex feasibility, operational, and enrollment data from multiple sources, translating findings into clear conclusions, insights, and actionable recommendations. Advanced proficiency in Excel and other data driven analysis tools, with experience structuring, analyzing, and presenting data to support feasibility assessments, benchmarking, and enrollment forecasting.
• Strong verbal and written communication skills, including the ability to clearly and confidently present complex, data driven analyses and recommendations to diverse stakeholder audiences, adjusting communication style and level of detail as appropriate. Demonstrated critical thinking and solution-oriented, creative problem solving skills.

What ICON can offer you

Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

Our benefits examples include:

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family’s needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

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