Principal Data Manager

Scorpion Therapeutics; United States; Remote; USD 140,000 - 200,000; Full time

Job summary

Scorpion Therapeutics in the United States is seeking a Principal Data Manager to oversee clinical data management across multiple bladder cancer-focused programs. You will lead data management from study start-up to database lock, shape data strategies, and ensure data quality and regulatory readiness.

The role requires a BS/BA in a scientific field and 12+ years in clinical data management within biotech, pharma, or CROs, with Phase I-III experience and vendor oversight.

Qualifications

• 12+ years in clinical data management within biotech, pharma, or CROs
• Experience across Phases I-III
• Leadership in developing departmental standards, SOPs, and governance

Responsibilities

• Lead all data management activities from study start-up to database lock
• Develop data strategies and standards to ensure data quality and regulatory readiness
• Manage vendor relationships and oversight for data management
• Design CRFs and data capture specifications
• Mentor and develop data management staff
• Provide strategic input for protocol development, risk mitigation, and process improvements

Skills

Leadership

Data management strategy

Vendor oversight

Regulatory compliance

CRF design

Education

BS/BA in a scientific field

Tools

CDISC standards

Job description

Role:

Principal Data Manager overseeing clinical data management across multiple bladder cancer-focused clinical programs.

Responsibilities:

Leading all data management activities from study start-up to database lock, developing data strategies and standards, managing vendor relationships, designing CRFs, ensuring data quality and compliance, and mentoring data management staff. Provides strategic input for protocol development, risk mitigation, and process improvements aligned with regulatory and inspection readiness.

Requirements:

BS/BA in a scientific field, 12+ years in clinical data management within biotech, pharma, or CROs, with extensive experience in Phase I-III trials, multi-study programs, and vendor oversight. Demonstrates leadership in developing departmental standards, SOPs, and governance.

High-value:

Focus on oncology (bladder cancer), clinical trials (Phases I-III), global study experience, vendor management, regulatory submission support, and industry best practices like CDISC.

Work setup:

Fully remote with comprehensive benefits.