Principal Clinical Scientist

Alignerr Corp.; Boston (MA); Remote; USD 14,000 - 55,000; Part time

Job summary

Alignerr Corp. is seeking a Principal Clinical Scientist to provide senior-level expertise in designing clinical trial protocols for regulator-ready data used in AI training and evaluation. You will interpret trial results to ensure accuracy and regulatory relevance, and assess AI analyses for scientific soundness in relation to FDA/EMA standards.

This is a fully remote hourly contract role. You will work independently, with flexible scheduling, contributing expert feedback to advance biomedical

Qualifications

• Senior-level clinical scientist with hands-on trial design experience
• Experience interpreting clinical data for regulatory submissions
• Strong grounding in biostatistics and translational science

Responsibilities

• Design and critically review clinical trial protocols for regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results for accuracy and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory alignment
• Provide expert feedback shaping how AI models reason about clinical data and outcomes
• Identify gaps between AI outputs and real-world regulatory expectations

Skills

Clinical trial design

Regulatory submissions

Biostatistics

Translational science

Independent remote work

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your career-long expertise in clinical trial design and regulatory science could directly influence how AI understands and evaluates medical evidence?

We're looking for a Principal Clinical Scientist to bring senior-level rigor to the AI systems being built at the frontier of biomedical research. You'll work alongside world-leading AI labs to ensure that clinical data powering next-generation AI models meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role — work on your own schedule, on your own terms.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and critically review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory standards
• Provide expert, structured feedback that directly shapes how AI models reason about clinical data, trial outcomes, and biomedical evidence
• Identify gaps, errors, or misalignments between AI outputs and real-world regulatory expectations

Who You Are

• Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or their international equivalents
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Rigorous, detail-oriented, and comfortable working independently on complex scientific material
• Clear and precise written communicator — you can articulate nuanced scientific judgment in structured formats

Nice to Have

• Prior experience with data annotation, data quality evaluation, or AI model assessment workflows
• Background in pharmacovigilance, medical affairs, or health technology assessment
• Familiarity with AI tools or scientific evaluation platforms as an end user

Why Join Us

• Work directly on frontier AI systems making a real impact in clinical and biomedical research
• Influence how the next generation of AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible — work when and where it suits you, with no fixed schedule
• Freelance autonomy with the substance of high-impact, expert-level scientific work
• Collaborate with leading AI research teams on problems that matter
• Potential for ongoing work and contract extension as new projects launch