Principal Cell Culture Process Scientist

Kelly; Bethesda (MD); On-site; USD 150,000 - 190,000; Full time

Job summary

Kelly Government Solutions is seeking a Principal Scientist, Cell Culture Process Development to support NIH in Bethesda, MD. The role leads development of cell culture processes for clinical candidates and enables tech transfer to clinical manufacturing.

The contractor will plan and conduct experiments, supervise lab activities, and collaborate with project teams to ensure regulatory readiness and timely delivery of results. A PhD and extensive culture experience are required.

Qualifications

• Ph.D. in Biochemistry, Chemical Engineering, or life sciences.
• Experience with mammalian and/or microbial cell culture development.
• Proficiency with Microsoft Outlook.

Responsibilities

• Supports the planning and execution of research experiments in the context of the laboratory's overall research program.
• Lead development of cell culture processes for clinical vaccine or therapeutic candidates, including process tech transfer for clinical grade material manufacture to enable clinical trials.
• Plan, design, and maintain execution of experiments that develop robust processes for toxicological grade material generation and scalable cGMP production.
• Serve as SME for tech transfer deliverables, regulatory submissions, and project planning.
• Establish production processes for cell culture workflows using advanced bioreactor systems and complex growth strategies.
• Drive innovation and adoption of new technologies (e.g., scalable tangential flow filtration-based transient transfection methods).
• Maintains laboratory equipment and the training of others in their use.
• Drive an upstream/cell culture project from conception to clinical manufacturing by developing processes requiring operation of bioreactors and other cell culture equipment and provide support as required.
• Maintains laboratory staff on research projects and techniques.
• Capture process development study results and process descriptions and results in lab notebooks and other technical documents to drive SOP generation, project review, and approval.
• Coordinates with junior staff to modify research protocols.
• Work with Principal Investigators in scheduling and prioritizing instrument usage.

Skills

Cell culture development

Mammalian & microbial culture

Education

PhD in life sciences

Tools

Outlook

Job description

Kelly Government Solutions is seeking a Principal Scientist, Cell Culture Process Development to support NIH in Bethesda, MD. The role leads development of cell culture processes for clinical candidates and enables tech transfer to clinical manufacturing.

The contractor will plan and conduct experiments, supervise lab activities, and collaborate with project teams to ensure regulatory readiness and timely delivery of results. A PhD and extensive culture experience are required.