Principal Biocatalysis Scientist Data-Driven Enzyme Design

Merck; Rahway (NJ); On-site; USD 173,000 - 273,000; Full time

Job summary

Merck & Co., Rahway, NJ, is seeking a Principal Scientist to expand data science-driven biocatalysis capabilities and lab automation across the pipeline. You will lead interdisciplinary teams and develop novel enzymes for sustainable manufacturing within SMPR&D, collaborating with chemists, biologists, and IT professionals.

The role emphasizes leadership, collaboration, and mentoring, with a strong track record in biocatalysis, enzyme engineering, and automated workflows to accelerate discovery

Qualifications

• Ph.D./M.S./B.S. in a related field with multi-year industry experience.
• Experience in biocatalysis and enzyme engineering.
• Experience using Benchling for data capture and workflow support.

Responsibilities

• Provide scientific leadership and collaborate with cross-functional teams.
• Develop enzymes and biocatalytic processes for small-molecule synthesis.
• Implement digital tools and automation to accelerate workflows.
• Lead AI/ML and data-driven design initiatives.
• Mentor scientists and communicate results to the organization.

Skills

Biocatalysis

Enzyme engineering

Data science

Python

SQL

Automation

Team leadership

Mentoring

Communication

Education

Ph.D./M.S./B.S. in related field

Tools

Benchling

Biomolecular automation (Biomek)

Biomek

Firefly

Dragonfly

Mantis

Job description

Merck & Co., Rahway, NJ, is seeking a Principal Scientist to expand data science-driven biocatalysis capabilities and lab automation across the pipeline. You will lead interdisciplinary teams and develop novel enzymes for sustainable manufacturing within SMPR&D, collaborating with chemists, biologists, and IT professionals.

The role emphasizes leadership, collaboration, and mentoring, with a strong track record in biocatalysis, enzyme engineering, and automated workflows to accelerate discovery