Preclinical Scientist, Transdermal PK & Skin Studies

Terrestrial Bio, Inc.; Woburn (MA); On-site; USD 110,000 - 130,000; Full time

Job summary

Terrestrial Bio, Inc. seeks a PhD-level scientist to own the scientific side of preclinical studies, designing and analyzing in vivo and ex vivo experiments and reporting their implications.

You will work with the in vivo team, study manager, and stakeholders to answer critical questions with data-driven insights. Responsibilities include designing studies, characterizing skin, analyzing variability, performing PK and statistics, writing study reports, and contributing to regulatory documents.

Qualifications

• PhD in Biomedical Engineering, Pharmacology, or related field with 2+ years of relevant experience.
• Demonstrated noncompartmental PK analysis and statistical analysis of biological variability.
• Experience designing in vivo studies and determining endpoints and group sizes.
• Hands-on tissue mechanical testing or ex vivo tissue models is a plus.
• Strong scientific writing with study reports/publications.
• Programming in R or Python is preferred; exposure to IND-enabling work is a plus.
• Ability to clearly present data to scientific and non-scientific audiences.

Responsibilities

• Design in vivo and ex vivo study protocols, endpoints, sampling schedules, and analysis plans.
• Lead skin property study design and analysis.
• Quantify variability and identify sources to inform experimental design.
• Perform PK and statistical analyses and present findings to the program team.
• Write study reports and contribute to regulatory document sections.
• Provide scientific oversight to ongoing studies and coordinate with cross-functional teams.

Skills

Quantitative analysis

Study design

Tissue characterization

Scientific writing

Programming in R/Python

Data analysis (PK)

Communication

Education

PhD in Biomedical Engineering

PhD in Pharmacology

Tools

Phoenix WinNonlin

Job description

Terrestrial Bio, Inc. seeks a PhD-level scientist to own the scientific side of preclinical studies, designing and analyzing in vivo and ex vivo experiments and reporting their implications.

You will work with the in vivo team, study manager, and stakeholders to answer critical questions with data-driven insights. Responsibilities include designing studies, characterizing skin, analyzing variability, performing PK and statistics, writing study reports, and contributing to regulatory documents.