Postdoctoral Scientist

Texas Biomedical Research Institute; San Antonio (TX); On-site; USD 60,000 - 85,000; Full time

Benefits offered by this job

Comprehensive health, dental, vision,

Life insurance

Competitive retirement plan with 6%

Paid holidays and Winter Recess

Volunteer Time Off

Paid parental leave

Flexible work arrangements

On-site medical clinic

On-site fitness center

Relaxed dress code

Professional development and tuition"

Job summary

The Sharan Lab at Texas Biomedical Research Institute is seeking a motivated postdoctoral scholar to study host-pathogen interactions in TB/HIV co-infection using small and large animal models in BSL3. The role involves conducting immunology and single-cell RNA sequencing studies, designing experiments, and collaborating across teams to advance mechanistic insights.

Ideal candidates hold a PhD in Immunology or related field with at least one year of BSL3 TB research, including flow cytometry and

Qualifications

• PhD in Immunology or closely related discipline from an accredited university.
• At least 1 year of BSL3 and TB-related research, including immunology, flow cytometry and scRNA-seq.
• First-author papers in peer-reviewed journals and excellent communication skills.

Responsibilities

• Designs the study with the supervisor and conducts scientific research with other team members.
• Conducts BSL3 experiments on animal models, including flow cytometry, CFU plating, pathological analyses, cytokine analyses, confocal microscopy and viral RNA quantification.
• Analyzes data and reports to the supervisor in real time.
• Prepares or assists in preparation of material for publication.
• Prepares or assists in the preparation of grant applications.
• Participates in seminars and scientific meetings appropriate to the field.

Skills

Immunology research

Flow cytometry

Single-cell RNA sequencing

Animal models

Scientific writing

Education

PhD in Immunology or related field

Tools

Confocal microscopy

Job description

Description

The Sharan Lab is hiring an enthusiastic postdoctoral scholar to study host-pathogen interactions in TB/HIV co-infection in our lab. Sharan Lab is interested in understanding the mechanisms by which HIV reactivates a latent TB infection using small and large animal models in BSL3. We use immunology, pathology and single cell RNAseq techniques to perform detailed mechanistic studies. This role will help conduct NHP and mouse experiments to study host-directed therapy in TB/HIV co-infection.

Primary Role:

• Designs the study with the supervisor and conducts scientific research with other team members.


• Conducts BSL3 experiments on animal models, including flow cytometry, CFU plating, pathological analyses, cytokine analyses, confocal microscopy and viral RNA quantification.


• Analyzes data and reports to supervisor real-time.


• Prepares or assist in preparation of material for publication.


• Prepares or assist in the preparation of grant applications.


• Participates in seminars and scientific meetings appropriate to field of interest.

Our Ideal Candidate:

A highly motivated individual with a Doctoral Degree in Immunology or a closely related discipline from an accredited college or university. The ideal candidate will have at least 1 year of BSL3 and TB-related research, including immunology, flow cytometry and scRNA-seq. The candidate must have first-author papers in peer-reviewed scientific journals. The research role will be highly collaborative. The candidate should have excellent written and oral communication skills. The candidate should have ability to handle multiple projects, have exceptional organizational skills and should be a tram player. The candidate should be willing to work in a BSL3 lab space and should be experienced working with animal models.

What We Can Offer You!

• Enjoy an employee-centered culture grounded in open communication, empowerment, and trust. We believe in working hard and having fun, offering 100+ culture events each year to bring our team together and keep the energy strong!


• Comprehensive health, dental, vision, and life insurance coverage for you and your family—including pet insurance options.


• Competitive employer-funded retirement plan with 6% contributions starting on day one, increasing with years of service.


• Generous paid time off, including 14 paid holidays and a paid Winter Recess (from the last week of December through New Year's).


• Paid time off for short-term illness and mental wellness, helping you take the time you need when life happens.


• Volunteer Time Off (VTO) to encourage giving back to the community.


• Paid parental leave to support you and your growing family.


• Flexible work arrangements that support a strong work-life balance.


• On-site medical clinic, wellness incentives, and prescription support programs designed to make care more accessible and affordable.


• On-site fitness center and wellness programs to help you stay active and healthy.


• Relaxed dress code so you can feel comfortable and be yourself at work.


• Dynamic learning environment with professional development opportunities, mentorship, tuition reimbursement, and leadership programs to support your growth.


• Proud recipient of the 2025 Healthy Workplace Platinum Recognition from the San Antonio Business Group on Health (SABGH)-the highest honor for employee-focused wellness initiatives.

Who We Are!

Texas Biomedical Research Institute is one of the world's leading independent biomedical research institutions dedicated to advancing global human health through innovative biomedical research. Texas Biomed aims to unravel the mysteries of infectious diseases through innovative thinking, creative problem solving and cutting-edge technologies.

Texas Biomed is the only independent, nonprofit infectious disease research institute in the U.S. to combine:

• The highest-level biocontainment labs for infectious disease and biodefense research


• A federally-designated National Primate Research Center


• More than 80 years of discoveries advancing diagnostics, vaccines and therapies


• An entrepreneurial culture and specialized expertise in regulated science required for FDA approval

We take pride in fostering a culture of respect, opportunity, and unity! Texas Biomedical Research Institute provides equal employment opportunities for all qualified employees and applicants without regard to race, color, sex, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or other legally protected status.