Postdoctoral Scholar - Cancer Institute

The Pennsylvania State University; United States; On-site; USD 55,000 - 75,000; Full time

Benefits offered by this job

Competitive benefits

Job summary

The Pennsylvania State University invites applications for a postdoctoral position in the Mineishi lab at Penn State Hershey Medical Center. The project will develop chimeric antigen receptor T-cells for hematological malignancies and explore genomic structural variances linked to leukemia.

Ideal candidates hold an MD and PhD or equivalent, with a strong background in hematology/oncology and molecular biology.

Qualifications

• MD and PhD or equivalent required.
• Strong background in hematology/oncology and molecular biology.
• Experience with genomic data analysis and experimental design preferred.

Responsibilities

• Develop and analyze CAR-T cell projects for hematological malignancies.
• Contribute to clinical trial management and data analysis.
• Assist in grant writing and supervision of research staff and students.
• Publish results in national journals and collaborate with cross-disciplinary teams.

Skills

Molecular biology

Genomic data analysis

Data analysis

Hematology/oncology

Grant writing

Experiment design

Publication record

Research supervision

English fluency

Education

MD and PhD or equivalent

Job description

Contract and Remote Work

Approval of remote and hybrid work is not guaranteed regardless of work location. For additional information on remote work at Penn State, see Notice to Out of State Applicants.

This is a term position; length of the term will be discussed during the interview process. Continuation past the term length discussed will be based on university need, performance, and/or availability of funding.

Position Specifications

A postdoctoral position is available in the laboratory of Shin Mineishi, MD, Professor and Director Bone and Marrow Transplant Program, Penn State Hershey Medical Center, Penn State College of Medicine, and Penn State Cancer Institute.

Projects will involve developing chimeric antigen receptor T-cells targeting hematological malignancies. This project will be performed in collaboration with Dr. Daniel Hayes, Department Head of Biomedical Engineering Dorothy Foehr Huck and J. Lloyd Huck Chair in Nanotherapeutics and Regenerative Medicine. Other project will include identifying genomic structural variances associated with leukemia incidence, focusing on leukemia's molecular markers.

Projects will be performed in collaboration with James Broach, Ph.D., Distinguished Professor and Chair Department of Biochemistry and Molecular Biology Institute for Personalized Medicine. The lab will use human blood samples, bone marrow samples, clinical data, and publicly available datasets. We will also measure molecular markers of leukemia patients and incorporate molecular biology techniques including micro-RNA to correlate with leukemia pathogenesis.

In addition, candidates need to work on clinical trial management which we are currently ongoing related to leukemia treatment.

Candidates will be supervised by Dr. Mineishi as well as Dr. Kentaro Minagawa, MD, PhD, Associate Professor of Medicine.

Candidates should be highly motivated, have a keen attention to detail and follow protocols, have an MD and Ph.D. or equivalent, and possess a strong background in hematology/oncology, molecular biology, and data analysis. Specific experience and skills in the analysis of genomic data, including structural variances, are preferred. Prior experience with basic laboratory techniques is desirable. The candidate should be capable of designing and analyzing experiments consistent with the broad thematic goals of the research program. The candidate should have quality publications in nationally recognized journals, be fluent in English, and be interested and motivated to contribute to grant writing and supervision of research associates and students as the laboratory expands.

Candidates must submit a current CV and a cover letter to be considered for this position.

Background Checks / Clearances

This position requires the following clearances in addition to applicable background checks: PA State Police Criminal Background Check, PA Child Abuse History Clearance Form, and Federal (FBI) Fingerprint Criminal Background Check.

Benefits

Penn State provides a competitive benefits package for full-time employees designed to support both personal and professional well-being. For more detailed information, please visit our Benefits Page. (Note: For Postdoctoral benefits, please see our Postdoctoral Benefits page.)

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