Postdoctoral Researcher, Translational Reproductive Biology

University of Pennsylvania; Pennsylvania; On-site; USD 60,000 - 70,000; Full time

Job summary

The University of Pennsylvania Perelman School of Medicine invites applications for a Postdoctoral Researcher in the OBGYN Research division. The lab focuses on implantation, endometrial regeneration, and gynecologic disease using human systems and organoid models.

The role emphasizes independent project ownership, collaboration with clinical and RNA biology groups, and training-oriented culture. Responsibilities include experimental design, molecular assays, imaging, data analysis, and

Qualifications

• PhD, MD, or equivalent advanced degree in reproductive biology, cell or molecular biology, immunology, physiology, bioengineering, or related field.
• Hands-on experience with mammalian tissue culture including sterile technique.
• Proficiency in core molecular biology assays and data interpretation.
• Ability to work independently and drive a project forward.
• Evidence of initiative, collaboration, and mentoring.
• Strong organizational and communication skills.
• Commitment to women's health and translational research.

Responsibilities

• Design, execute, and troubleshoot experiments using primary human reproductive tract tissue and patient-derived organoid models.
• Maintain and expand primary and organoid culture systems.
• Perform core molecular assays and sample preparation for bulk, single-cell, and spatial transcriptomics.
• Execute tissue-based imaging including IHC/immunofluorescence and multiplexed platforms.
• Analyze data with computational collaborators and interpret results.
• Document protocols and contribute to SOPs.
• Coordinate with clinical teams on tissue acquisition per IRB protocols.
• Prepare figures and presentations; present at meetings.
• Contribute to grants and career development funding.
• Mentor REI fellows, residents, students, and undergraduates.

Skills

Mammalian tissue culture

Organoid culture

Molecular assays

RNA/DNA extraction

RT-qPCR

Immunoblotting/ELISA

Independent project design

Mentoring juniors

Scientific communication

Collaborative research

Education

PhD, MD, or equivalent advanced degree

Tools

10x Genomics Multiome

Visium

CODEX imaging

Imaging (IHC/IF)

QuPath/ ImageJ

Flow cytometry

Job description

The University of Pennsylvania Perelman School of Medicine invites applications for a Postdoctoral Researcher in the OBGYN Research division. The lab focuses on implantation, endometrial regeneration, and gynecologic disease using human systems and organoid models.

The role emphasizes independent project ownership, collaboration with clinical and RNA biology groups, and training-oriented culture. Responsibilities include experimental design, molecular assays, imaging, data analysis, and