Postdoctoral Researcher - Biophysics

The Medical College of Wisconsin, Inc.; Wauwatosa (WI); On-site; USD 55,000 - 75,000; Full time

Job summary

The Vasquez-Vivar Lab in the Department of Biophysics at the Medical College of Wisconsin is seeking a highly motivated Postdoctoral Fellow to join our research team focused on fetal brain injury and the mechanisms of acquired motor disorders in children.

The position offers opportunities to lead projects using redox biology, biochemistry, and preclinical models in a collaborative, well-resourced environment.

Qualifications

• Ph.D. or candidate within 3 months of start date.
• Preferred PhD in Neuroscience, Biochemistry, Cell Biology or Molecular Biology.
• Hands-on protein analysis, stem cell culture, and microscopy experience preferred.

Responsibilities

• Perform in vitro transcription, qPCR, and protein sequencing analysis.
• Express, purify, and characterize mammalian recombinant enzymes.
• Conduct biochemical assays to study loss or gain of function in cells expressing mutant proteins.
• Isolate cells, perform cell culture, and conduct microscopy/immunofluorescence assays.
• Analyze data, contribute to manuscript preparation, and assist with grant proposals.

Skills

Biology

qPCR

Data analysis

Critical thinking

Education

Ph.D. or PhD candidate

Neuroscience / Biochemistry / Cell Biology / Molecular Biology

Tools

Enzyme assays

Microscopy

Docking analysis

Job description

SummaryThe Vasquez-Vivar Lab in the Department of Biophysics at the Medical College of Wisconsin is seeking a highly motivated Postdoctoral Fellow to join our research team focused on fetal brain injury and the mechanisms of acquired motor disorders in children. We use a multidisciplinary approach that integrates redox biology, biochemical, and preclinical models to explore gain- and loss-of-function relationships and identify opportunities for therapeutic perinatal interventions. This position offers an exciting opportunity for candidates passionate about redox cell biology, with the potential to develop novel experimental approaches and lead research projects in a collaborative and well-resourced environment.The Department of Biophysics at the Medical College of Wisconsin has a rich tradition of innovation and excellence in redox and structural biology and biomedical imaging, with strengths in EPR (electron paramagnetic resonance), NMR (nuclear magnetic resonance), and MRI (clinical magnetic resonance imaging). MCW is Wisconsin’s largest private research institution and the third-largest private medical school in the U.S. The institution fosters a collaborative environment that integrates basic science, clinical research, and education to advance biomedical knowledge and human health.Primary ResponsibilitiesPerform in vitro transcription, qPCR, and protein sequencing analysis.Complete expression, purification, and characterization of mammalian recombinant enzymes.Conduct biochemical assays to study loss or gain of function in cells expressing mutant proteins.Isolate cells from tissues, perform cell culture, and conduct microscopy/immunofluorescence assays.Analyze experimental data, interpret results, and contribute to manuscript preparation.Present research findings at lab meetings, institutional seminars, and scientific conferencesMentor and contribute to training and scientific development within the lab.Assist with the development of grant proposals and collaborative research initiatives.Other duties as assigned.Knowledge – Skills – AbilitiesRequired knowledge in biology, chemistry, mathematics, and statisticsDocumentation, records management and data utilization skillsComplex problem solving, critical thinking, and resource managementExcellent written and verbal communication skillsQualificationsMinimum Required Education: Ph.D. or PhD candidate within 3 months of the start dateMinimum Required Experience: 0 yearsPreferred Education: PhD in Neuroscience, Biochemistry, Cell Biology, Molecular Biology, or a related discipline.Preferred Experience: Hands-on experience in protein analysis, stem cell culture, and microscopy methods. Familiarity with enzyme-substrate docking analysis. Strong background in protein or redox signaling biochemistry. Proven ability to work independently, manage time effectively, and troubleshoot experiments. First-author publication record in peer-reviewed journalsInterested applicants should submit the following materials:Cover letter outlining research interests and career goalsCurriculum vitae (CV)Contact information for three professional referencesPhysical RequirementsWork requires occasionally lifting moderate weight materials, standing, or walking continuously.Work EnvironmentOccasional exposure to dust, noise, temperature changes, or contact with water or other liquids. Work is performed in an environmentally controlled environment.Sensory AcuityAbility to detect and translate speech or other communication required. May occasionally require the ability to distinguish colors and perceive relative distances between objects.Why MCW?Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options403B Retirement PackageCompetitive Vacation and Paid Holidays offeredTuition ReimbursementPaid Parental LeaveEmployee & Family Assistance Program (EFAP)Pet InsuranceOn campus Fitness Facility, offering onsite classesAdditional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.For a brief overview of our benefits see: Benefits OverviewFor a full list of positions see: MCW CareersAt MCW all of our endeavors, from our internal operations to our interactions with our partners, are driven by our shared organizational values: Caring – Collaborative – Curiosity – Inclusive – Integrity – Respect. We are committed to fostering an inclusive environment that values diversity in backgrounds, experiences, and perspectives through merit-based processes and in alignment with all applicable laws. We believe that embracing human differences is critical to realize our vision of a healthier world, and we recognize that a healthy and thriving community starts from within. Our values define who we are, what we stand for and how we conduct ourselves at MCW. If you believe in embracing individuality and working together according to these principles to improve health for all, then MCW is the place for you. For more information, please visit our institutional website.MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination:The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering an inclusive community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.