Postdoctoral Research Fellow (Herr; protein structure)

Cincinnati Children's; Cincinnati (OH); On-site; USD 55,000 - 70,000; Full time

Job summary

Cincinnati Children’s is seeking a postdoctoral fellow in the Immunobiology laboratory of Dr. Andrew Herr. The role focuses on structural analysis of proteins using Cryo Electron Microscopy or X-Ray Crystallography.

The position is full-time in Cincinnati, OH, with duties spanning experimental design, data analysis, and scientific communication. The ideal candidate will have a PhD/MD or equivalent and hands-on experience with advanced microscopy methods, contributing to high-impact research and

Qualifications

• PhD/MD or equivalent required.
• Experience with Cryo Electron Microscopy or X-ray crystallography for structural analysis of proteins.

Responsibilities

• Develop independence as a scientist through critical thinking, data analysis, and project planning.
• Design, execute, and record experiments and analyze data that may affect patient care decisions.
• Research and improve methods, ensure protocol accuracy, and troubleshoot laboratory equipment.

Skills

Cryo-EM

X-Ray Crystallography

Education

PhD/MD or equivalent

Tools

Cryo Electron Microscopy

X-Ray Crystallography

Job description

• Primary Location: Location S
• Department: Immunobiology
• Shift: Day (United States of America)
• Schedule: Full time
• Weekly Hours: 40
• FTE: 1
• Employee Status: Regular

There is an immediate opening for a highly skilled and motivated postdoctoral fellow in the laboratory of Dr. Andrew Herr. The candidate should have experience with Cryo Electron microscopy or X-Ray Crystallography for structural analysis of proteins.

MAJOR DUTIES AND RESPONSIBILITIES:

• Develop the skills and knowledge (critical thinking and analysis of data, devising specific aims, long‑term project planning and experimental design) to become an independent scientist
• Design, execute, and record laboratory experiments, and analyze data, which may affect decisions regarding future patient care.
• Research and improve current methods and evaluate innovative techniques. protocol and assay accuracy by conducting regular quality and reproducibility checks. Implement this knowledge in the Division/Department. Troubleshoot and correct erroneous results or problems with laboratory equipment.
• Discuss relevant insights about experimental results with Faculty and provide useful recommendations and analysis.
• Present research at laboratory meetings, journal clubs, seminars, and meetings. Develop skills to critically review and discuss data being presented.
• Draft, write, and edit scientific reports, papers, journal articles, abstracts, and grants.
• Progressively increasing responsibilities with mentorship of research staff and fiscal administration
• Maintain currency in field through continuing education, literature, and seminars. Be an active participant in the process through intellectual discussions with PI and other faculty, trainees and research staff. Solicit feedback on career trajectory from PI, mentoring committee and others who can provide coaching and insight.
• Attend required Cincinnati Children’s training sessions and ensure regulatory compliance with all institutional (i.e. Infection Control, ORCRA and others as applicable) policies and procedures
• Perform other duties as assigned.

Required:

• PhD/MD or equivalent

Preferred;

• Bacterial culture methods
• Advanced microscopy techniques
• Protein purification experience

About Us

At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.

Cincinnati Children's is:

• Recognized by U.S. News & World Report as a top 10 best Children’s Hospitals in the nation for more than 15 years
• Consistently among the top 3 Children’s Hospitals for National Institutes of Health (NIH) Funding
• Recognized as one of America’s Best Large Employers (2025) , America’s Best Employers for New Grads (2025)
• One of the nation’s America’s Most Innovative Companies as noted by Fortune
• Consistently certified as great place to work
• A Leading Disability Employer as noted by the National Organization on Disability
• Magnet® designated for the fourth consecutive time by the American Nurses Credentialing Center (ANCC)

We Embrace Innovation—Together. We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.

Comprehensive job description provided upon request.

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability